SCHEMBL754901

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753760	0.75	ALDH1A1 (0.42)	ALDH1A1MAPTHPGDKMT2AHTT
	SCHEMBL6195630	0.74	KDM4E (0.41)	ALDH1A1MAPTGAAKMT2AHDAC3
	SCHEMBL18472951	0.70	KMT2A (0.46)	ALDH1A1HPGDCYP3A4GAACYP2C9
	SCHEMBL26119158	0.69	BCL2L1 (0.47)	ALDH1A1MAPTHPGDCYP1A2CYP3A4
	SCHEMBL12000680	0.69	KMT2A (0.42)	ALDH1A1HPGDCYP3A4GAACYP2C9
	SCHEMBL11406747	0.69	KMT2A (0.36)	ALDH1A1MAPTHPGDCYP1A2CYP3A4
	SCHEMBL597442	0.67	IDO1 (0.46)	ALDH1A1KMT2AHDAC3HDAC4HDAC1
	SCHEMBL14944320	0.67	KMT2A (0.44)	ALDH1A1HPGDCYP3A4GAACYP2C9
	SCHEMBL3229698	0.67	NR4A1 (0.41)	MAPTKMT2AHTTHDAC3HDAC4
	SCHEMBL13015262	0.67	LMNA (0.37)	ALDH1A1MAPTHPGDKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.