SCHEMBL1301619

SCHEMBL1301619

CCC(C)CC(=O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.36
CA1 P00915 1/20 0.36
CA7 P43166 1/20 0.36
CA14 Q9ULX7 1/20 0.36
OR51E2 Q9H255 2/20 0.35
MAPT P10636 1/20 0.33
ELANE P08246 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPK1 P28482 1/20 0.32
SLC13A3 Q8WWT9 1/20 0.32
EGLN1 Q9GZT9 1/20 0.32
FFAR3 O14843 1/20 0.32
TSHR P16473 1/20 0.32
FFAR1 O14842 1/20 0.32
HAO1 Q9UJM8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2171974 1.00 CA2 (0.36) CA2CA1CA7CA14OR51E2
SCHEMBL16114175 0.86 OR51E2 (0.40) CA2OR51E2ALDH1A1TDP1MAPK1
SCHEMBL31346314 0.81 CA2 (0.37) CA2CA1CA7CA14MAPT
SCHEMBL1300587 0.80 TSHR (0.44) CA1TDP1TSHRHAO1
SCHEMBL23882614 0.79 OR51E2 (0.41) CA2OR51E2ALDH1A1TDP1MAPK1
SCHEMBL11328060 0.79 CES1 (0.39) CA2CA1CA7CA14ELANE
SCHEMBL28248821 0.79 SLC22A6 (0.39) OR51E2ALDH1A1TDP1MAPK1SLC13A3
SCHEMBL28248822 0.79 SLC22A6 (0.39) OR51E2ALDH1A1TDP1MAPK1SLC13A3
SCHEMBL14672577 0.79 GRIK1 (0.39) CA2CA1CA7CA14MAPT
SCHEMBL50835 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10450589-B2 Microbial synthesis of aldehydes and corresponding alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2019-10-22 US claimed
EP-2686432-B1 MICROBIAL SYNTHESES OF ALDEHYDES AND CORRESPONDING ALCOHOLS EASEL BIOTECHNOLOGIES LLC (US) 2018-12-26 EP claimed
US-20170283836-A1 Microbial Synthesis Of Aldehydes And Corresponding Alcohols EASEL BIOTECHNOLOGIES, LLC 2017-10-05 US claimed
US-9708631-B2 Microbial synthesis of aldehydes and corresponding alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2017-07-18 US claimed
EP-2346991-B1 PRODUCTION OF C5-C8 ALCOHOLS USING EVOLVED ENZYMES AND METABOLICALLY ENGINEERED MICROORGANISMS UNIV CALIFORNIA (US) 2016-12-28 EP claimed
US-20160130611-A1 Microbial Synthesis Of Aldehydes And Corresponding Alcohols EASEL BIOTECHNOLOGIES, LLC 2016-05-12 US claimed
US-9206443-B2 Microbial synthesis of aldehydes and corresponding alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2015-12-08 US claimed
EP-2686432-A2 MICROBIAL SYNTHESES OF ALDEHYDES AND CORRESPONDING ALCOHOLS Easel Biotechnologies, LLC (US) 2014-01-22 EP claimed
US-20140011231-A1 Microbial Synthesis Of Aldehydes And Corresponding Alcohols EASEL BIOTECHNOLOGIES, LLC (US) 2014-01-09 US claimed
US-8298798-B2 Production of C5-C8 alcohols using evolved enzymes and metabolically engineered microorganisms THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-10-30 US claimed
WO-2012125688-A2 MICROBIAL SYNTHESES OF ALDEHYDES AND CORRESPONDING ALCOHOLS EASEL BIOTECHNOLOGIES, LLC (US) 2012-09-20 WO claimed
US-20110201083-A1 PRODUCTION OF C5-C8 ALCOHOLS USING EVOLVED ENZYMES AND METABOLICALLY ENGINEERED MICROORGANISMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-08-18 US claimed
EP-2346991-A2 PRODUCTION OF C5-C8 ALCOHOLS USING EVOLVED ENZYMES AND METABOLICALLY ENGINEERED MICROORGANISMS The Regents Of The University Of California (US) 2011-07-27 EP claimed
WO-2010045629-A2 PRODUCTION OF C5-C8 ALCOHOLS USING EVOLVED ENZYMES AND METABOLICALLY ENGINEERED MICROORGANISMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-04-22 WO claimed
US-5854035-A Enzyme with leuDH activity, nucleotide sequence coding therefor and process for the prepartion of the enzyme DEGUSSA AG (DE) 1998-12-29 US claimed
EP-0792933-A2 Enzyme having LeuDH activity, nucleotide sequence coding therefor and process for the preparation of this enzyme Degussa Aktiengesellschaft (DE) 1997-09-03 EP claimed
CN-118028837-A Amino Acid Synthesis Method 中山大学 2024-05-14 CN disclosed
US-20210171688-A1 BIOCOMPATIBLE COPOLYMER, CURABLE COMPOSITION, BIOCOMPATIBLE COATING LAYER AND BIOCOMPATIBLE DEVICE INCLUDING THE SAME NATIONAL CENTRAL UNIVERSITY (TW) 2021-06-10 US disclosed
US-5854035-A Enzyme with leuDH activity, nucleotide sequence coding therefor and process for the prepartion of the enzyme DEGUSSA AG (DE) 1998-12-29 US disclosed
EP-0792933-A2 Enzyme having LeuDH activity, nucleotide sequence coding therefor and process for the preparation of this enzyme Degussa Aktiengesellschaft (DE) 1997-09-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201083-A1 PRODUCTION OF C5-C8 ALCOHOLS USING EVOLVED ENZYMES AND METABOLICALLY ENGINEERED MICROORGANISMS ADH5, ADH1C, ADH1A CA2 4048/4885CA1 2977/4885CA7 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.