Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
| ▸ | ALPI | P09923 | 2/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153670 | 0.88 | ALDH1A1 (0.48) | ALPLALPIENPP1KMT2ACA12 | |
| SCHEMBL7248801 | 0.77 | ALDH1A1 (0.60) | ALPLALPIENPP1KMT2ACA12 | |
| SCHEMBL3776213 | 0.73 | ALDH1A1 (0.40) | KMT2ACA2KDM4EALDH1A1HPGD | |
| SCHEMBL13016940 | 0.72 | TSSK1B (0.43) | ALPLALPIKMT2ACYP1A2KDM4E | |
| SCHEMBL26625027 | 0.70 | ENPP1 (0.55) | ALPLALPIENPP1KMT2ACA12 | |
| SCHEMBL5083041 | 0.67 | MEN1 (0.58) | KMT2ACA12CA2ALDH1A1HPGD | |
| SCHEMBL2057491 | 0.65 | KMT2A (0.57) | KMT2ACYP1A2PTPN1CA12CA2 | |
| SCHEMBL6939225 | 0.64 | MEN1 (0.55) | KMT2ACA12CA2ALDH1A1HPGD | |
| SCHEMBL8499431 | 0.64 | ALPI (0.53) | ALPLALPIENPP1KMT2ACYP1A2 | |
| SCHEMBL26624926 | 0.64 | FUT7 (0.61) | ENPP1KMT2ACA12CA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2010-12-23 | — | — | US | disclosed |
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | TBCB, TBC1D15, TBC1D5 | ALPL 3483/4885ALPI 1838/4885ENPP1 1074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.