Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13016765 | 0.88 | ALPL (0.41) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL7248801 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL7247052 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL3777051 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL13016939 | 0.72 | TSSK1B (0.51) | ALDH1A1KDM4EHSD17B10HPGDKMT2A | |
| SCHEMBL3778800 | 0.72 | ALDH1A1 (0.65) | ALDH1A1KDM4EHSD17B10HPGDALOX15 | |
| SCHEMBL9573720 | 0.70 | ALDH1A1 (0.47) | ALDH1A1HPGDKMT2AHTTALPL | |
| SCHEMBL26625027 | 0.70 | ENPP1 (0.55) | KMT2AALPIALPLCA12CA1 | |
| SCHEMBL5670908 | 0.69 | MAOB (0.58) | ALDH1A1KDM4EHSD17B10HPGDALPI | |
| SCHEMBL5671449 | 0.69 | MAOB (0.45) | ALDH1A1KDM4EKMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | INSTITUTE OF MATARIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2010-12-23 | — | — | US | disclosed |
| US-20030176494-A1 | Novel coumarin and chromene compounds and methods of preparation and use thereof for treating or preventing viral infections | ADVANCED LIFE SCIENCES, INC. | 2003-09-18 | — | — | US | disclosed |
| WO-2003070159-A2 | NOVEL COUMARIN AND CHROMENE COMPOUNDS AND METHODS OF TREATING OR PREVENTING VIRAL INFECTIONS | SARAWAK MEDICHEM PHARMACEUTICALS (US) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324067-A1 | TETRACYCLIC DIPYRANO-COUMARIN COMPOUNDS WITH ANTI-HIV AND ANTI-MYCOBACTERIUM TUBERCULOSIS ACTIVITIES | TBCB, TBC1D15, TBC1D5 | ALDH1A1 482/4885KDM4E 3237/4885HSD17B10 159/4885 |
| US-20030176494-A1 | Novel coumarin and chromene compounds and methods of preparation and use thereof for treating or preventing viral infections | HAVCR2, PROC, CTRC | ALDH1A1 2199/4885KDM4E 3488/4885HSD17B10 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.