Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 18/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.82 |
| ▸ | RAB9A | P51151 | 2/20 | 0.82 |
| ▸ | BLM | P54132 | 2/20 | 0.82 |
| ▸ | MAPT | P10636 | 2/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.82 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.78 |
| ▸ | HTT | P42858 | 2/20 | 0.78 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.78 |
| ▸ | ACHE | P22303 | 1/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.78 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29664993 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL23270615 | 1.00 | TOP1 (1.00) | TOP1ALDH1A1GLAMEN1KMT2A | |
| Camptothecin SCHEMBL29056181 | 0.96 | TOP1 (0.92) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL27561956 | 0.92 | TOP1 (1.00) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL1006662 | 0.92 | TOP1 (1.00) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL27489142 | 0.91 | TOP1 (0.85) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL3847426 | 0.91 | TOP1 (0.85) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL1062768 | 0.91 | TOP1 (1.00) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL27502037 | 0.91 | TOP1 (1.00) | TOP1ALDH1A1GLAMEN1KMT2A | |
| SCHEMBL6848647 | 0.90 | TOP1 (0.84) | TOP1ALDH1A1GLAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4743124-A1 | DE-N-ACETYLATED POLYSIALIC ACID (DPSA) BINDING AGENT, CONJUGATES, AND METHOD OF USING SAME | Saccharo, Inc. (US) | 2026-05-20 | — | — | EP | claimed |
| CN-122055170-A | Des-N-acetylated polysialic acid (dPSA) binders, conjugates, and methods of use thereof | 萨克罗有限公司 | 2026-05-15 | — | — | CN | claimed |
| WO-2026086871-A1 | ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING | Centre for Translational Stem Cell Biology Limited (CN) | 2026-04-30 | — | — | WO | claimed |
| WO-2025015281-A1 | DE-N-ACETYLATED POLYSIALIC ACID (DPSA) BINDING AGENT, CONJUGATES, AND METHOD OF USING SAME | SACCHARO, INC. (US) | 2025-01-16 | — | — | WO | claimed |
| CN-117343944-A | Gene, protein, recombinant vector and method for catalyzing synthesis of 9-methoxy camptothecine | 上海师范大学 | 2024-01-05 | — | — | CN | claimed |
| CN-116463302-A | Camptothecine 9-hydroxylase NtCPT9H and NnCPT9H as well as genes and application thereof | 中国科学院昆明植物研究所 | 2023-07-21 | — | — | CN | claimed |
| CN-115429773-A | Method for preparing medicine nano crystal preparation | 复旦大学 | 2022-12-06 | — | — | CN | claimed |
| WO-2022120490-A1 | CYTOCHROME P450 MONOOXYGENASES AND USES THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2022-06-16 | — | — | WO | claimed |
| CN-113880872-A | Preparation of camptothecin boric acid compound and application of camptothecin boric acid compound in anti-tumor aspect | 兰州大学 | 2022-01-04 | — | — | CN | claimed |
| CN-113880855-A | Preparation of 9-fluoro camptothecin derivative and application of 9-fluoro camptothecin derivative in anti-tumor aspect | 兰州大学 | 2022-01-04 | — | — | CN | claimed |
| EP-1270579-B1 | PROCESS FOR PRODUCING CAMPTOTHECIN | YAKULT HONSHA KK (JP) | 2006-05-31 | — | — | EP | claimed |
| CN-1228341-C | Process for producing camptothecin | YAKULT HONSHA KK (JP) | 2005-11-23 | — | — | CN | claimed |
| US-6743918-B2 | HYDROLYZING 9-METHOXYCAMPTOTHECIN; 9-O-PERFLUORO-ALKYL-SULFONYLATION OR 9-O-PHENYLTETRAZOLYLATION FOLLOWED BY HYDROGENOLYSIS; LOW COST; SIMPLE | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2004-06-01 | — | — | US | claimed |
| US-20040087609-A1 | PROCESS FOR PRODUCING CAMPTOTHECIN | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2004-05-06 | — | — | US | claimed |
| CN-1419558-A | Process for preparing camptothecin | YAKULT HONSHA KK (JP) | 2003-05-21 | — | — | CN | claimed |
| EP-1270579-A1 | PROCESS FOR PRODUCING CAMPTOTHECIN | Kabushiki Kaisha Yakult Honsha (JP) | 2003-01-02 | — | — | EP | claimed |
| EP-0436653-A4 | SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF | — | 1992-01-15 | — | — | EP | claimed |
| EP-0436653-A1 | SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF | RESEARCH TRIANGLE INSTITUTE (US) | 1991-07-17 | — | — | EP | claimed |
| US-4981968-A | ENZYME INHIBITORS, ANTITUMOR | RESEARCH TRIANGLE INSTITUTE (US) | 1991-01-01 | — | — | US | claimed |
| WO-1990003169-A1 | SYNTHESIS OF CAMPTOTHECIN AND ANALOGS THEREOF | RESEARCH TRIANGLE INSTITUTE (US) | 1990-04-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087609-A1 | PROCESS FOR PRODUCING CAMPTOTHECIN | PFAS, TOP2A, TOP2B | TOP1 4/4885ALDH1A1 3180/4885GLA 3277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.