Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571313 | 0.87 | GABRA1 (0.55) | GABRA1GABRB2TAAR1HTR1ADAO | |
| SCHEMBL13019660 | 0.82 | GABRA1 (0.39) | GABRA1GABRB2PDK2 | |
| SCHEMBL172963 | 0.79 | — | — | |
| SCHEMBL1517219 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2TAAR1ALDH1A1HTT | |
| SCHEMBL20542550 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2TAAR1IDO1HTR1A | |
| SCHEMBL30029990 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2TAAR1ALDH1A1HTT | |
| SCHEMBL19085450 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2TAAR1IDO1HTR1A | |
| SCHEMBL8346814 | 0.78 | GABRA1 (0.46) | GABRA1GABRB2TAAR1IDO1HTR1A | |
| SCHEMBL21286977 | 0.78 | LIPG (0.40) | TAAR1CYP2D6CYP2C9KCNH2 | |
| SCHEMBL12086036 | 0.77 | TAAR1 (0.50) | GABRA1GABRB2TAAR1IDO1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210104682-A1 | ORGANIC LIGHT-EMITTING DEVICE AND DEVICE INCLUDING SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-04-08 | — | — | US | disclosed |
| CN-110002930-A | A kind of method of hydrogenating reduction alkenyl aroma halo derivatives | 浙江大学 | 2019-07-12 | — | — | CN | disclosed |
| WO-2017035349-A1 | AMIDE COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2017-03-02 | — | — | WO | disclosed |
| US-20100316567-A1 | ETHER AND ALKYL PHOSPHOLIPID COMPOUNDS FOR TREATING CANCER AND IMAGING AND DETECTION OF CANCER STEM CELLS | CELL ACQUISITION CORP. | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100316567-A1 | ETHER AND ALKYL PHOSPHOLIPID COMPOUNDS FOR TREATING CANCER AND IMAGING AND DETECTION OF CANCER STEM CELLS | PHOSPHO1, PEBP1, SGMS1 | GABRA1 3675/4885GABRB2 4153/4885TAAR1 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.