Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22306130 | 0.85 | GABRA1 (0.55) | GABRA1GABRB2KAT6ADAOMEN1 | |
| SCHEMBL26586553 | 0.81 | TAAR1 (0.37) | TAAR1IDO1 | |
| SCHEMBL13977269 | 0.81 | TAAR1 (0.46) | TAAR1IDO1 | |
| SCHEMBL29581622 | 0.79 | TAAR1 (0.35) | GABRA1GABRB2TAAR1IDO1 | |
| SCHEMBL1222461 | 0.79 | APOBEC3G (0.37) | GABRA1GABRB2TAAR1IDO1PDK2 | |
| SCHEMBL17580222 | 0.79 | TAAR1 (0.35) | GABRA1GABRB2TAAR1IDO1 | |
| SCHEMBL7764711 | 0.78 | LIPG (0.47) | MEN1MAPTKMT2APTGS2HTT | |
| SCHEMBL9723219 | 0.78 | GABRA1 (0.32) | GABRA1GABRB2RIPK1 | |
| SCHEMBL13019656 | 0.78 | GABRA1 (0.48) | GABRA1GABRB2TAAR1IDO1HTR1A | |
| SCHEMBL266645 | 0.78 | RIPK1 (0.49) | GABRA1GABRB2KAT6ATAAR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263550-B1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL CORP (JP) | 2020-11-25 | — | — | EP | disclosed |
| WO-2017116928-A1 | FUSED TRICYCLIC HETEROCYCLIC COMPOUNDS AS HIV INTEGRASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-07-06 | — | — | WO | disclosed |