Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 14/20 | 0.58 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.57 |
| ▸ | EGFR | P00533 | 9/20 | 0.56 |
| ▸ | ABL1 | P00519 | 7/20 | 0.56 |
| ▸ | ABL2 | P42684 | 6/20 | 0.56 |
| ▸ | LCK | P06239 | 3/20 | 0.55 |
| ▸ | KDR | P35968 | 3/20 | 0.55 |
| ▸ | TEK | Q02763 | 3/20 | 0.55 |
| ▸ | FYN | P06241 | 2/20 | 0.55 |
| ▸ | LYN | P07948 | 2/20 | 0.55 |
| ▸ | CSK | P41240 | 2/20 | 0.55 |
| ▸ | BTK | Q06187 | 2/20 | 0.55 |
| ▸ | PLK4 | O00444 | 1/20 | 0.55 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.55 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.55 |
| ▸ | PAK4 | O96013 | 1/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20351777 | 0.84 | SRC (0.66) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL13020005 | 0.84 | SRC (0.78) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL23966721 | 0.83 | RIPK2 (0.71) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL29999029 | 0.83 | RIPK2 (0.71) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL8320765 | 0.83 | SRC (0.75) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL13020339 | 0.82 | RET (0.66) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL8320799 | 0.82 | SRC (0.81) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL13020342 | 0.81 | SRC (0.56) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL13020337 | 0.81 | SRC (0.72) | SRCRIPK2EGFRABL1ABL2 | |
| SCHEMBL20351637 | 0.80 | SRC (0.65) | SRCRIPK2EGFRABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | FOLDRX PHARMACEUTICALS, INC. (US) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331297-A1 | MODULATION OF PROTEIN TRAFFICKING | RAB1A, COPB1, GOLT1B | SRC 1332/4885RIPK2 2849/4885EGFR 3921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.