Diphenylether

Diphenylether

SCHEMBL130202

O=S(=O)(Cl)Cl.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.67
TSHR P16473 1/20 0.67
CA1 P00915 2/20 0.58
CA2 P00918 2/20 0.58
CA9 Q16790 2/20 0.58
SOS1 Q07889 1/20 0.58
PGR P06401 4/20 0.52
HTT P42858 3/20 0.52
LMNA P02545 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
NSD2 O96028 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HKDC1 Q2TB90 1/20 0.48
TLR9 Q9NR96 1/20 0.48
ALDH1A1 P00352 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL11375805 0.90 LTA4H (0.60) LTA4HTSHRCA1CA2CA9
SCHEMBL3114864 0.89 PGR (0.62) LTA4HTSHRCA1CA2CA9
SCHEMBL7425961 0.87 CA1 (0.52) LTA4HTSHRCA1CA2CA9
SCHEMBL27506658 0.87 HTT (0.72) LTA4HTSHRCA1CA2CA9
SCHEMBL3109435 0.87 LTA4H (0.75) LTA4HTSHRCA1CA2CA9
SCHEMBL6512870 0.87 LTA4H (0.50) LTA4HTSHRCA1CA2CA9
SCHEMBL27479068 0.87 FFAR1 (0.60) LTA4HTSHRCA1CA2CA9
SCHEMBL9536733 0.84 SOS1 (0.64) LTA4HTSHRCA1CA2CA9
SCHEMBL31244 0.84 SOS1 (0.64) LTA4HTSHRCA1CA2CA9
Diphenylether SCHEMBL387430 0.83 LTA4H (0.67) LTA4HTSHRCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4226955-A None JP disclosed
CN-118105923-A Production process and equipment of 4,4' -oxo-bis-benzenesulfonyl hydrazide 嘉兴市金利化工有限责任公司 2024-05-31 CN disclosed
CN-116178721-A Method for preparing polyether sulfone 湖南理工学院 2023-05-30 CN disclosed
CN-115819768-A Reversible adhesive polysulfide and preparation method thereof 广东工业大学 2023-03-21 CN disclosed
CN-111534097-A Formula and preparation method of high-temperature-resistant special engineering plastic 江苏百通塑业发展有限公司 2020-08-14 CN disclosed
CN-111423640-A Anti-aging wear-resistant modified styrene-butadiene rubber for power cables in mining areas 赵银红 2020-07-17 CN disclosed
CN-111171569-A Polyphenylene sulfide/polyether sulfone wear-resistant composite board and preparation method thereof 庄盛光 2020-05-19 CN disclosed
US-20150218366-A1 FLAME-RETARDANT POLYESTER RESIN COMPOSITIONS KANEKA CORPORATION (JP) 2015-08-06 US disclosed
US-20140336326-A1 ELECTRIC/ELECTRONIC COMPONENT USING FLAME-RETARDANT POLYESTER-BASED RESIN COMPOSITION KANEKA CORPORATION (JP) 2014-11-13 US disclosed
EP-2784119-A1 ELECTRICAL ELECTRONIC COMPONENT USING FLAME RETARDANT POLYESTER RESIN COMPOSITION Kaneka Corporation (JP) 2014-10-01 EP disclosed
EP-0176325-B1 LIGHT SENSITIVE SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1990-04-04 EP disclosed
EP-0358662-A1 POLYARYLETHERS AND PROCESS THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-21 EP disclosed
EP-0358662-A4 POLYARYLETHERS AND PROCESS THEREFOR. DU PONT (US) 1990-01-23 EP disclosed
US-4801657-A Process for producing polyarylethers by forming an alkylated intermediate E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-01-31 US disclosed
WO-1988007561-A1 POLYARYLETHERS AND PROCESS THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-06 WO disclosed
US-4670375-A USE OF MONODISPERSED SILVER HALIDE GRAINS AND INCREASED CONCENTRATION IN EMULSION LAYER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-06-02 US disclosed
US-4593086-A From carboxylic acid halide and aromatic dicarboxylic acid dihalide RAYCHEM CORPORATION (US) 1986-06-03 US disclosed
EP-0178183-A2 Preparation of aromatic ketone-sulfone copolymers RAYCHEM CORPORATION (a Delaware corporation) (US) 1986-04-16 EP disclosed
EP-0176325-A2 Light sensitive silver halide color photographic material KONICA CORPORATION (JP) 1986-04-02 EP disclosed
US-4247682-A DOUBLE ENDCAPPING BY AN ELECTROPHILIC AND A NUCLEOPHILIC END GROUP OF A POLYMER PREPARED BY AN ELECTRONEGITIVELY SUBSTITUTED AROMATIC ACID HALIDE OR SULFONYL HALIDE; MOLECULAR WEIGHT CONTROL; HEAT RESISTANCE RAYCHEM CORPORATION (US) 1981-01-27 US disclosed