Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | BMP1 | P13497 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.49 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 2/20 | 0.46 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.46 |
| ▸ | IL23R | Q5VWK5 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | CCKAR | P32238 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13021048 | 0.98 | MMP1 (0.54) | MMP1BMP1CASP1CASP3CASP7 | |
| SCHEMBL13020158 | 0.92 | CASP1 (0.51) | MMP1CASP1CASP3CASP7MMP2 | |
| SCHEMBL14417484 | 0.91 | CASP1 (0.54) | MMP1CASP1CASP3CASP7MMP2 | |
| SCHEMBL13020893 | 0.91 | CASP1 (0.54) | MMP1CASP1CASP3CASP7MMP2 | |
| SCHEMBL13020765 | 0.88 | TACR1 (0.53) | CASP1CASP3CASP7MMP2MMP8 | |
| SCHEMBL13912384 | 0.85 | HDAC8 (0.53) | MMP1CASP1CASP3CASP7MMP2 | |
| SCHEMBL13912385 | 0.84 | GHSR (0.49) | MMP1CASP1CASP3CASP7MMP2 | |
| SCHEMBL13021030 | 0.84 | GHSR (0.49) | MMP1CASP1CASP3CASP7MMP2 | |
| SCHEMBL10316474 | 0.82 | CASP1 (0.56) | MMP1CASP1CASP3CASP7MMP2 | |
| SCHEMBL14015903 | 0.81 | CASP1 (0.55) | MMP1CASP1CASP3CASP7MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100323969-A1 | Compounds Binding to P-Selectin | ASTELLAS PHARMA EUROPE B.V. (NL) | 2010-12-23 | — | — | US | disclosed |
| US-20090062186-A1 | Compounds Binding To P-Selectin | YAMANOUCHI ERUOPE B.V. (NL) | 2009-03-05 | — | — | US | disclosed |
| US-20090062186-A1 | Compounds Binding To P-Selectin | YAMANOUCHI ERUOPE B.V. (NL) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062186-A1 | Compounds Binding To P-Selectin | SELP, SELPLG, SELL | MMP1 2655/4885BMP1 3655/4885CASP1 1958/4885 |
| US-20100323969-A1 | Compounds Binding to P-Selectin | SELP, SELPLG, SELL | MMP1 2655/4885BMP1 3655/4885CASP1 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.