Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.53 |
| ▸ | ITGAL | P20701 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 3/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.49 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13020893 | 1.00 | CASP1 (0.54) | CASP1CASP3CASP7ITGB2ICAM1 | |
| SCHEMBL13912384 | 0.94 | HDAC8 (0.53) | CASP1CASP3CASP7ITGB2ICAM1 | |
| SCHEMBL13020765 | 0.93 | TACR1 (0.53) | CASP1CASP3CASP7ITGB2ICAM1 | |
| SCHEMBL13020158 | 0.93 | CASP1 (0.51) | CASP1CASP3CASP7EDNRAMMP2 | |
| SCHEMBL13020664 | 0.91 | MMP1 (0.52) | CASP1CASP3CASP7EDNRAMMP2 | |
| SCHEMBL13021048 | 0.89 | MMP1 (0.54) | CASP1CASP3CASP7EDNRAMMP2 | |
| SCHEMBL13912385 | 0.86 | GHSR (0.49) | CASP1CASP3CASP7EDNRAMMP2 | |
| SCHEMBL13021030 | 0.86 | GHSR (0.49) | CASP1CASP3CASP7EDNRAMMP2 | |
| SCHEMBL31171653 | 0.86 | CASP1 (0.58) | CASP1CASP3CASP7EDNRAMMP2 | |
| SCHEMBL10316474 | 0.85 | CASP1 (0.56) | CASP1CASP3CASP7EDNRAMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273951-B2 | Polyhydroxy phenols and their use in binding p-selectin | ASTELLAS PHARMA INC. (JP) | 2007-09-25 | — | — | US | disclosed |
| US-7273951-B2 | Polyhydroxy phenols and their use in binding p-selectin | ASTELLAS PHARMA INC. (JP) | 2007-09-25 | — | — | US | disclosed |