Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 10/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12979139 | 0.94 | TRPV4 (0.37) | TRPV4RAB9AKMT2A | |
| SCHEMBL13021921 | 0.93 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL12979418 | 0.93 | TRPV4 (0.33) | TRPV4 | |
| SCHEMBL3480108 | 0.93 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL13021140 | 0.92 | MCHR1 (0.34) | TRPV4RAB9A | |
| SCHEMBL13022857 | 0.92 | KMT2A (0.35) | TRPV4RAB9AALDH1A1KMT2A | |
| SCHEMBL3480088 | 0.92 | PTGDR2 (0.35) | TRPV4RAB9AALDH1A1 | |
| SCHEMBL12979498 | 0.92 | TRPV4 (0.34) | TRPV4RAB9AKMT2A | |
| SCHEMBL12979512 | 0.91 | XDH (0.33) | TRPV4 | |
| SCHEMBL3480317 | 0.90 | XDH (0.33) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | 92229129 QUEBEC INC. (CA) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317625-A1 | NOVEL SULFONAMIDOMETHYLPHOSPHONATE INHIBITORS OF BETA-LACTAMASE | MGAM, BPGM, PPME1 | TRPV4 4778/4885RAB9A 1592/4885ALDH1A1 2755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.