SCHEMBL13023261

SCHEMBL13023261

COc1cc(C)ccc1N1c2ccccc2S(=O)(=O)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.53
LMNA P02545 3/20 0.46
TP53 P04637 1/20 0.46
MAPT P10636 5/20 0.41
ACHE P22303 1/20 0.41
MGLL Q99685 1/20 0.41
GAA P10253 1/20 0.40
ADCY2 Q08462 1/20 0.39
ALDH1A1 P00352 1/20 0.38
G6PD P11413 1/20 0.38
TLR9 Q9NR96 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022507 0.92 POLB (0.51) POLBLMNATP53MAPTMGLL
SCHEMBL13021687 0.88 MGLL (0.47) POLBLMNATP53MAPTMGLL
SCHEMBL13023676 0.86 POLB (0.45) POLBLMNATP53MAPTMGLL
SCHEMBL12190946 0.86 POLB (0.46) POLBLMNATP53MAPTMGLL
SCHEMBL13023342 0.84 POLB (0.48) POLBLMNATP53MAPTMGLL
SCHEMBL13023280 0.81 LMNA (0.50) POLBLMNATP53MAPTMGLL
SCHEMBL18361205 0.81 AR (0.43) POLBMAPTMGLLG6PDTLR9
SCHEMBL13023848 0.80 POLB (0.40) POLBLMNAMAPTGAAADCY2
SCHEMBL13023507 0.80 POLB (0.41) POLBLMNAMAPTACHEGAA
SCHEMBL13022500 0.79 MAPT (0.48) POLBLMNATP53MAPTMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 POLB 2141/4885LMNA 1808/4885TP53 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.