SCHEMBL13023342

SCHEMBL13023342

COc1cc(C)cc(OC)c1N1c2ccccc2S(=O)(=O)c2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.48
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
MAPT P10636 5/20 0.42
MGLL Q99685 1/20 0.38
RXFP1 Q9HBX9 1/20 0.37
KDM4E B2RXH2 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023743 0.86 POLB (0.41) POLBLMNATP53MAPTMGLL
SCHEMBL13023261 0.84 POLB (0.53) POLBLMNATP53MAPTMGLL
SCHEMBL12190946 0.81 POLB (0.46) POLBLMNATP53MAPTMGLL
SCHEMBL2500153 0.81 LMNA (0.47) POLBLMNATP53MAPTRXFP1
SCHEMBL13023898 0.80 MEN1 (0.36) POLBMAPTKDM4EKMT2AALDH1A1
SCHEMBL13022507 0.78 POLB (0.51) POLBLMNATP53MAPTMGLL
SCHEMBL13023540 0.77 SLC40A1 (0.36) POLBMAPTKDM4EKMT2A
SCHEMBL13024142 0.77 POLB (0.39) POLBLMNAMAPTKMT2AALDH1A1
SCHEMBL13023445 0.76 MGLL (0.41) LMNAMAPTMGLLALDH1A1
SCHEMBL13023452 0.75 ACHE (0.37) LMNAMAPTMGLLKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 POLB 2141/4885LMNA 1808/4885TP53 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.