SCHEMBL13023919

SCHEMBL13023919

COc1cc(C)ccc1N1c2ccccc2C(=O)Oc2c1oc1ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
ADCY2 Q08462 1/20 0.40
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
GAA P10253 1/20 0.39
NPC1 O15118 3/20 0.39
AR P10275 1/20 0.38
CYP3A4 P08684 4/20 0.38
ALDH1A1 P00352 4/20 0.38
TSHR P16473 3/20 0.38
CYP2C19 P33261 3/20 0.38
HPGD P15428 3/20 0.38
HSD17B10 Q99714 3/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP2C9 P11712 2/20 0.38
THRB P10828 1/20 0.38
MAPK1 P28482 2/20 0.38
GMNN O75496 1/20 0.38
RAF1 P04049 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13022841 0.89 KMT2A (0.49) MEN1KMT2AMAPTLMNAGAA
SCHEMBL13023946 0.88 ALDH1A1 (0.41) MEN1KMT2AMAPTLMNANPC1
SCHEMBL13023844 0.87 ADCY2 (0.37) MEN1KMT2AADCY2MAPTLMNA
SCHEMBL13023912 0.86 LMNA (0.40) MAPTLMNAGAACYP3A4ALDH1A1
SCHEMBL13022128 0.86 MEN1 (0.48) MEN1KMT2AMAPTLMNAGAA
SCHEMBL13023926 0.84 KDM4E (0.44) MEN1KMT2AMAPTNPC1CYP3A4
SCHEMBL13023920 0.80 LMNA (0.35) MEN1KMT2AMAPTLMNAGAA
SCHEMBL13022830 0.79 KDM4E (0.42) MEN1KMT2AMAPTLMNANPC1
SCHEMBL13022846 0.78 KDM4E (0.50) MEN1KMT2AMAPTNPC1CYP3A4
SCHEMBL13023954 0.78 PIK3CD (0.37) LMNAKDM4EMAPK1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MEN1 725/4885KMT2A 2070/4885ADCY2 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.