SCHEMBL13023985

SCHEMBL13023985

Cc1cc(C)c(N2c3ccncc3Oc3ccncc32)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 13/20 0.34
MAPT P10636 2/20 0.33
RAPGEF4 Q8WZA2 2/20 0.32
NPC1 O15118 3/20 0.31
RAB9A P51151 3/20 0.31
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023975 0.94 RAPGEF4 (0.34) MAPTRAPGEF4NPC1RAB9ATP53
SCHEMBL13023971 0.94 MAPT (0.35) PIM1MAPTRAPGEF4NPC1RAB9A
SCHEMBL13024005 0.93 PIM1 (0.33) PIM1MAPTRAPGEF4MEN1KMT2A
SCHEMBL13023991 0.91 RAPGEF4 (0.32) MAPTRAPGEF4NPC1RAB9ATP53
SCHEMBL13023980 0.90 MAPT (0.36) MAPTRAPGEF4NPC1RAB9ATP53
SCHEMBL13023978 0.90 MAPT (0.36) PIM1MAPTRAPGEF4TP53SMN1; SMN2
SCHEMBL13024008 0.83
SCHEMBL13023993 0.83
SCHEMBL13024009 0.83 PIM1 (0.31) PIM1
SCHEMBL13024003 0.83 CYP17A1 (0.32) NPC1RAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 PIM1 33/4885MAPT 2367/4885RAPGEF4 3709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.