SCHEMBL13023978

SCHEMBL13023978

Cc1cc(C)c(N2c3ccccc3Oc3cnccc32)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
P2RX4 Q99571 4/20 0.35
PIM1 P11309 9/20 0.33
FLT3 P36888 1/20 0.33
GSK3B P49841 1/20 0.33
TP53 P04637 1/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023971 0.93 MAPT (0.35) MAPTSMN1; SMN2PIM1TP53RAPGEF4
SCHEMBL13023980 0.92 MAPT (0.36) MAPTSMN1; SMN2NPSR1P2RX4FLT3
SCHEMBL13023985 0.90 PIM1 (0.34) MAPTSMN1; SMN2PIM1TP53RAPGEF4
SCHEMBL13024005 0.89 PIM1 (0.33) MAPTPIM1RAPGEF4
SCHEMBL13023330 0.87 P2RX4 (0.42) MAPTSMN1; SMN2NPSR1P2RX4TP53
SCHEMBL13023983 0.86 MAPT (0.38) MAPTSMN1; SMN2NPSR1P2RX4TP53
SCHEMBL13023969 0.84 KMT2A (0.32) MAPTSMN1; SMN2PIM1TP53
SCHEMBL13023975 0.84 RAPGEF4 (0.34) MAPTSMN1; SMN2TP53RAPGEF4
SCHEMBL13023991 0.82 RAPGEF4 (0.32) MAPTSMN1; SMN2TP53RAPGEF4
SCHEMBL13024006 0.80 PIM1 (0.32) MAPTPIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 MAPT 2367/4885SMN1; SMN2 1804/4885NPSR1 2345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.