SCHEMBL13023975

SCHEMBL13023975

Cc1cc(C)c(N2c3cnccc3Oc3ccncc32)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
CYP17A1 P05093 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
NPC1 O15118 3/20 0.31
RAB9A P51151 3/20 0.31
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13023985 0.94 PIM1 (0.34) RAPGEF4KMT2AMEN1MAPTNPC1
SCHEMBL13023991 0.94 RAPGEF4 (0.32) RAPGEF4KMT2AMEN1MAPTNPC1
SCHEMBL13023980 0.93 MAPT (0.36) RAPGEF4MAPTCYP17A1NPC1RAB9A
SCHEMBL13023971 0.87 MAPT (0.35) RAPGEF4KMT2AMEN1MAPTCYP17A1
SCHEMBL13024005 0.87 PIM1 (0.33) RAPGEF4KMT2AMEN1MAPT
SCHEMBL13023992 0.86 CYP17A1 (0.32) CYP17A1
SCHEMBL13023972 0.85 KMT2A (0.32) KMT2AMAPTNPC1RAB9ATP53
SCHEMBL13023993 0.85
SCHEMBL13024008 0.85
SCHEMBL13023988 0.85 LMNA (0.38) MAPTNPC1RAB9ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286360-A1 POLYMER COMPOUND AND POLYMER LIGHT EMITTING DEVICE USING THE SAME IGF1R, SCO2, CRY1 RAPGEF4 3709/4885KMT2A 2070/4885MEN1 725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.