Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123554 | 0.94 | MAPT (0.33) | NPC1ALDH1A1MAPTGFERHSD17B10 | |
| SCHEMBL20733382 | 0.92 | — | — | |
| SCHEMBL17657394 | 0.89 | — | — | |
| SCHEMBL862637 | 0.79 | ALDH1A1 (0.37) | NPC1ALDH1A1MAPTGFERHSD17B10 | |
| SCHEMBL20733365 | 0.79 | — | — | |
| SCHEMBL20733381 | 0.79 | — | — | |
| SCHEMBL20733418 | 0.77 | — | — | |
| SCHEMBL769261 | 0.77 | MEN1 (0.30) | MAPT | |
| SCHEMBL16546614 | 0.77 | HSD17B1 (0.33) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL17657361 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842758-B2 | Conjugated materials featuring proquinoidal units | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-11-30 | — | — | US | disclosed |
| US-7842758-B2 | Conjugated materials featuring proquinoidal units | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-11-30 | — | — | US | disclosed |
| US-20090221762-A1 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | THE TRUSSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-09-03 | — | — | US | disclosed |
| US-20090221762-A1 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | THE TRUSSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221762-A1 | NOVEL CONJUGATED MATERIALS FEATURING PROQUINOIDAL UNITS | PML, ILK, PARG | NPC1 1297/4885ALDH1A1 2833/4885MAPT 83/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.