Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | GLP1R | P43220 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23696405 | 0.97 | CASP2 (0.44) | CASP2GLP1RMEN1KMT2ACA12 | |
| SCHEMBL19277702 | 0.97 | CASP2 (0.44) | CASP2GLP1RMEN1KMT2ACA12 | |
| SCHEMBL13025474 | 0.90 | MEN1 (0.40) | GLP1RMEN1KMT2ATSHRRECQL | |
| SCHEMBL25029532 | 0.89 | MEN1 (0.44) | GLP1RMEN1KMT2ATSHRRECQL | |
| SCHEMBL13024334 | 0.87 | ALDH1A1 (0.40) | GLP1RMEN1KMT2ATSHRRECQL | |
| SCHEMBL13024561 | 0.86 | MEN1 (0.39) | GLP1RMEN1KMT2ATSHRRECQL | |
| SCHEMBL13034773 | 0.86 | CES2 (0.43) | CASP2GLP1RMEN1KMT2ATSHR | |
| SCHEMBL13024335 | 0.86 | MEN1 (0.39) | GLP1RMEN1KMT2ATSHRRECQL | |
| SCHEMBL13815853 | 0.86 | CASP2 (0.56) | CASP2GLP1RTSHRRECQL | |
| SCHEMBL14685606 | 0.86 | CASP2 (0.43) | CASP2GLP1RMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317057-A1 | SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES | NOVO NORDISK A/S (DK) | 2010-12-16 | — | — | US | disclosed |