Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 8/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23696405 | 1.00 | CASP2 (0.44) | CASP2MEN1KMT2AGLP1RCA12 | |
| SCHEMBL13024328 | 0.97 | CASP2 (0.42) | CASP2MEN1KMT2AGLP1RCA12 | |
| SCHEMBL23157527 | 0.88 | CASP2 (0.46) | CASP2MEN1KMT2ACA12CA1 | |
| SCHEMBL21106543 | 0.88 | MEN1 (0.47) | MEN1KMT2AGLP1RCA12CA1 | |
| SCHEMBL24684540 | 0.88 | FAAH (0.51) | CASP2GLP1R | |
| SCHEMBL10048529 | 0.88 | CASP2 (0.55) | CASP2MEN1KMT2ACA12CA1 | |
| SCHEMBL13025474 | 0.87 | MEN1 (0.40) | MEN1KMT2AGLP1R | |
| SCHEMBL24943603 | 0.85 | CASP2 (0.43) | CASP2MEN1KMT2ACA12CA1 | |
| SCHEMBL25029532 | 0.85 | MEN1 (0.44) | MEN1KMT2AGLP1R | |
| SCHEMBL26059048 | 0.84 | SMN1; SMN2 (0.37) | MEN1KMT2AGLP1RCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017143059-A1 | MAX BINDERS AS MYC MODULATORS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-08-24 | — | — | WO | disclosed |