Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12013656 | 0.92 | TSHR (0.50) | HPGDSMN1; SMN2HTTTSHRGLP1R | |
| SCHEMBL4828881 | 0.88 | TSHR (0.58) | HPGDSMN1; SMN2HTTTSHRGLP1R | |
| SCHEMBL13640847 | 0.80 | HPGD (0.43) | HPGDSMN1; SMN2HTTTSHRGLP1R | |
| SCHEMBL13640968 | 0.80 | GLP1R (0.47) | HPGDSMN1; SMN2HTTTSHRGLP1R | |
| SCHEMBL4270058 | 0.80 | CNR1 (0.44) | HPGDTSHRGLP1RMEN1KMT2A | |
| SCHEMBL4264199 | 0.80 | TSHR (0.69) | HPGDSMN1; SMN2HTTTSHRALDH1A1 | |
| SCHEMBL12090657 | 0.80 | TSHR (0.69) | HPGDSMN1; SMN2HTTTSHRALDH1A1 | |
| SCHEMBL25108952 | 0.79 | TSHR (0.62) | HPGDSMN1; SMN2HTTTSHRALDH1A1 | |
| SCHEMBL25108979 | 0.79 | TSHR (0.62) | HPGDSMN1; SMN2HTTTSHRALDH1A1 | |
| SCHEMBL25108941 | 0.79 | TSHR (0.62) | HPGDSMN1; SMN2HTTTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100284956-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
| US-20100284956-A1 | HAIR COSMETIC COMPOSITION | KAO CORPORATION (JP) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100284956-A1 | HAIR COSMETIC COMPOSITION | ADH1A, ADH1C, H1-0 | HPGD 1593/4885SMN1; SMN2 4530/4885HTT 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.