SCHEMBL12013656

SCHEMBL12013656

COCCOCCNC(=O)CCCCCCC(C)CCCCC(C)CCCCCCC(=O)NCCOCCOC

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.50
▸ HPGD P15428 3/20 0.49
▸ HTT P42858 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ GLP1R P43220 8/20 0.43
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.41
▸ CNR1 P21554 2/20 0.41
▸ ENPP2 Q13822 1/20 0.39
▸ LPAR1 Q92633 1/20 0.39
▸ LPAR2 Q9HBW0 1/20 0.39
▸ CNR2 P34972 1/20 0.38
▸ EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4828881 0.96 TSHR (0.58) TSHRHPGDHTTSMN1; SMN2GLP1R
SCHEMBL13027126 0.92 HPGD (0.43) TSHRHPGDHTTSMN1; SMN2GLP1R
SCHEMBL4270058 0.87 CNR1 (0.44) TSHRHPGDGLP1RMEN1KMT2A
SCHEMBL12090657 0.86 TSHR (0.69) TSHRHPGDHTTSMN1; SMN2MEN1
SCHEMBL4264199 0.86 TSHR (0.69) TSHRHPGDHTTSMN1; SMN2MEN1
SCHEMBL25108979 0.86 TSHR (0.62) TSHRHPGDHTTSMN1; SMN2MEN1
SCHEMBL25108941 0.86 TSHR (0.62) TSHRHPGDHTTSMN1; SMN2MEN1
SCHEMBL25108952 0.86 TSHR (0.62) TSHRHPGDHTTSMN1; SMN2MEN1
SCHEMBL23787581 0.85 TSHR (0.67) TSHRHPGDHTTSMN1; SMN2MEN1
SCHEMBL4828890 0.84 TSHR (0.71) TSHRHPGDHTTSMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252272-B2 Hair cosmetic composition KAO CORPORATION (JP) 2012-08-28 — — US disclosed
US-8252272-B2 Hair cosmetic composition KAO CORPORATION (JP) 2012-08-28 — — US disclosed
EP-1433464-B1 Hair cleansing composition KAO CORP (JP) 2011-08-24 — — EP disclosed
US-7897143-B2 Amphipathic amide lipid, anionic surfactant, and acid or salt; feel, moisture retention, smoothness, stability; shampoo KAO CORPORATION (JP) 2011-03-01 — — US disclosed
US-7897143-B2 Amphipathic amide lipid, anionic surfactant, and acid or salt; feel, moisture retention, smoothness, stability; shampoo KAO CORPORATION (JP) 2011-03-01 — — US disclosed
US-7892526-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-02-22 — — US disclosed
US-7862806-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-01-04 — — US disclosed
US-7862806-B2 Hair cosmetic composition KAO CORPORATION (JP) 2011-01-04 — — US disclosed
US-7842101-B2 Oxidative hair dye composition KAO CORPORATION (JP) 2010-11-30 — — US disclosed
US-7842100-B2 Two-part oxidative hair dye composition KAO CORPORATION (JP) 2010-11-30 — — US disclosed
US-20090047231-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2009-02-19 — — US disclosed
US-20090047231-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2009-02-19 — — US disclosed
US-20080299063-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2008-12-04 — — US disclosed
US-20080299063-A1 HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2008-12-04 — — US disclosed
US-7351716-B2 Dermatological preparations KAO CORPORATION (JP) 2008-04-01 — — US disclosed
US-7351716-B2 Dermatological preparations KAO CORPORATION (JP) 2008-04-01 — — US disclosed
US-20070166272-A1 HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME KAO CORPORATION (JP) 2007-07-19 — — US disclosed
US-20070166272-A1 HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME KAO CORPORATION (JP) 2007-07-19 — — US disclosed
EP-1808157-A1 Hair cosmetic compositions and process for producing the same Kao Corporation (JP) 2007-07-18 — — EP disclosed
WO-2007064042-A1 AQUEOUS HAIR COSMETIC COMPOSITION KAO CORPORATION (JP) 2007-06-07 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299063-A1 HAIR COSMETIC COMPOSITION H1-0, H1-3, H1-2 TSHR 807/4885HPGD 2551/4885HTT 421/4885
US-20090047231-A1 AQUEOUS HAIR COSMETIC COMPOSITION POLR1C, CUTA, POLH TSHR 794/4885HPGD 3204/4885HTT 285/4885
US-20070166272-A1 HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME CUTA, SHH, POLR1C TSHR 983/4885HPGD 3646/4885HTT 390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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