SCHEMBL13030145

SCHEMBL13030145

O=[N+]([O-])c1ccc2c(ccn2C2CC(O)C(CO)O2)c1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SLC29A1 Q99808 1/20 0.47
▸ TYMS P04818 1/20 0.43
▸ ADRB1 P08588 1/20 0.42
▸ DNMT1 P26358 1/20 0.42
▸ LMNA P02545 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ ALOX12 P18054 1/20 0.40
▸ ADRA1A P35348 1/20 0.40
▸ TK1 P04183 1/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ THPO P40225 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ PMP22 Q01453 1/20 0.40
▸ HBB P68871 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2946371 1.00 SLC29A1 (0.47) SLC29A1TYMSADRB1DNMT1LMNA
SCHEMBL12732344 1.00 SLC29A1 (0.47) SLC29A1TYMSADRB1DNMT1LMNA
SCHEMBL10183365 1.00 SLC29A1 (0.47) SLC29A1TYMSADRB1DNMT1LMNA
SCHEMBL21067741 0.86 TYMS (0.58) TYMS
SCHEMBL21067742 0.86 TYMS (0.58) TYMS
SCHEMBL13030152 0.81 SLC29A1 (0.47) SLC29A1TYMSADRB1DNMT1CYP1A2
SCHEMBL14534827 0.81 LMNA (0.49) SLC29A1LMNASMN1; SMN2CYP1A2NFKB1
SCHEMBL14084325 0.81 LMNA (0.49) SLC29A1LMNASMN1; SMN2CYP1A2NFKB1
SCHEMBL1062447 0.81 LMNA (0.49) SLC29A1LMNASMN1; SMN2CYP1A2NFKB1
SCHEMBL29446054 0.81 LMNA (0.49) SLC29A1LMNASMN1; SMN2CYP1A2NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4611764-A1 ANTIBIOTIC-RESISTANT ARTIFICIAL NUCLEOSIDE, COMPOSITION AND METHOD Cleveland State University (US) 2025-09-10 — — EP claimed
WO-2024097151-A1 ANTIBIOTIC-RESISTANT ARTIFICIAL NUCLEOSIDE, COMPOSITION AND METHOD CLEVELAND STATE UNIVERSITY (US) 2024-05-10 — — WO claimed
EP-4611764-A1 ANTIBIOTIC-RESISTANT ARTIFICIAL NUCLEOSIDE, COMPOSITION AND METHOD Cleveland State University (US) 2025-09-10 — — EP disclosed
WO-2024097151-A1 ANTIBIOTIC-RESISTANT ARTIFICIAL NUCLEOSIDE, COMPOSITION AND METHOD CLEVELAND STATE UNIVERSITY (US) 2024-05-10 — — WO disclosed
US-9096835-B2 DNA polymerase MEDICAL RESEARCH COUNCIL (GB) 2015-08-04 — — US disclosed
US-9096835-B2 DNA polymerase MEDICAL RESEARCH COUNCIL (GB) 2015-08-04 — — US disclosed
US-20100292471-A1 PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME PANAGENE INC. (KR) 2010-11-18 — — US disclosed
US-20100292471-A1 PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME PANAGENE INC. (KR) 2010-11-18 — — US disclosed
US-20090305292-A1 DNA POLYMERASE MEDICAL RESEARCH COUNCIL (GB) 2009-12-10 — — US disclosed
US-20090305292-A1 DNA POLYMERASE MEDICAL RESEARCH COUNCIL (GB) 2009-12-10 — — US disclosed
US-20070020653-A1 DNA polymerase MEDICAL RESEARCH COUNCIL 2007-01-25 — — US disclosed
US-20070020653-A1 DNA polymerase MEDICAL RESEARCH COUNCIL 2007-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070020653-A1 DNA polymerase POLN, POLH, POLI SLC29A1 2257/4885TYMS 87/4885ADRB1 3733/4885
US-20100292471-A1 PEPTIDE NUCLEIC ACID OLIGOMERS COMPRISING UNIVERSAL BASES,PREPARATION METHODS THEREOF, AND KITS, DEVICES AND METHODS FOR THE ANALYSIS, DETECTION OR MODULATION OF NUCLEIC ACIDS USING THE SAME ADAR, POLM, POLRMT SLC29A1 163/4885TYMS 769/4885ADRB1 4708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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