SCHEMBL130304

SCHEMBL130304

Brc1ccccc1Oc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.52
TSHR P16473 2/20 0.52
LMNA P02545 1/20 0.48
GAA P10253 1/20 0.48
KMT2A Q03164 1/20 0.48
HRH1 P35367 1/20 0.45
CTNNB1 P35222 1/20 0.45
ALDH1A1 P00352 2/20 0.44
HTT P42858 2/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
RIPK1 Q13546 1/20 0.44
HPGD P15428 1/20 0.44
NTRK1 P04629 1/20 0.42
NTRK3 Q16288 1/20 0.42
NTRK2 Q16620 1/20 0.42
KDM1A O60341 2/20 0.42
HTR1A P08908 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4859489 0.98 LTA4H (0.50) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL28857814 0.95 TSHR (0.48) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL8954758 0.95 LTA4H (0.55) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL74839 0.92 ALDH1A1 (0.52) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL3843172 0.90 ALDH1A1 (0.50) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL8954774 0.89 MAOB (0.48) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL5567756 0.87 NCOA1 (0.47) LTA4HTSHRLMNAGAAKMT2A
SCHEMBL3839158 0.86 ALDH1A1 (0.44) LMNAGAAKMT2AALDH1A1HTT
SCHEMBL3845666 0.86 SLC6A4 (0.53) TSHRLMNAKMT2AALDH1A1HTT
SCHEMBL3841096 0.85 ALDH1A1 (0.50) LTA4HTSHRGAAKMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1788 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118974133-A Two part room temperature curable heat and flame resistant composition 汉高股份有限及两合公司 2024-11-15 CN claimed
CN-118179592-A Preparation method and application of bromodiphenyl oxide composite catalyst 安徽泰达新材料股份有限公司 2024-06-14 CN claimed
EP-4371623-A1 METHOD FOR PHOTOLYTIC DEGRADATION OF BROMINATED FLAME RETARDANTS IN A PLASTIC - APPARATUS THEREFOR CREPIM (FR) 2024-05-22 EP claimed
CN-117723694-A Method for detecting C3 content of candesartan cilexetil intermediate in candesartan cilexetil 河南省药品医疗器械检验院(河南省疫苗批签中心) 2024-03-19 CN claimed
CN-117705980-A Method for determining content of sartan bromodiphenyl oxide in candesartan cilexetil tablet 河南省药品医疗器械检验院(河南省疫苗批签中心) 2024-03-15 CN claimed
CN-113024832-B Gas adsorption composite material, flame-retardant HIPS composite material and display equipment 海信视像科技股份有限公司 2022-05-27 CN claimed
CN-107666904-B Purified composition of polyunsaturated fatty acids, method for preparing same and use thereof 提贝托·布鲁泽塞 2022-02-01 CN claimed
CN-113817439-A Flame-retardant modified silicone building sealant and preparation method thereof 山东福瑞斯新材料科技有限公司 2021-12-21 CN claimed
CN-110146695-B Method for screening human transthyretin interferent by adopting k nearest neighbor algorithm 南京理工大学 2021-12-10 CN claimed
CN-113041540-A Composite explosion suppressant for suppressing zinc powder explosion and preparation method thereof 山东科技大学 2021-06-29 CN claimed
EP-0290860-A2 Thermosetting resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1988-11-17 EP claimed
EP-0144015-B1 SELF-EXTINGUISHING COMPOSITIONS BASED ON ETHYLENE VINYLACETATE COPOLYMERS SUITABLE FOR THE PREPARATION OF FOAMED MATERIALS MONTEDIPE S.p.A. (IT) 1988-09-14 EP claimed
EP-0144178-B1 CYANOACRYLATE ADHESIVE COMPOSITION HAVING SUSTAINED TOUGHNESS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-08-17 EP claimed
CN-86103093-A PREPARATION PROCESS OF POLYBROMODIPHENYL ETHER 1987-11-18 CN claimed
EP-0062210-B1 THERMOPLASTIC POLYURETHANE ELASTOMER BEING POOR IN HALOGEN BY THE ADDITION OF A FOUR-ADDITIVES COMBINATION, ITS PREPARATION AND ITS USE BAYER AG (DE) 1986-05-14 EP claimed
US-4532278-A Extruded polyolefin fiber containing aromatic bromine compound, dialkylsubstituted/hydroxybenzyl/isocyanurate HANCOCK HENRY 1985-07-30 US claimed
EP-0144015-A1 Self-extinguishing compositions based on ethylene vinylacetate copolymers suitable for the preparation of foamed materials MONTEDIPE S.p.A. (IT) 1985-06-12 EP claimed
EP-0144178-A1 Cyanoacrylate adhesive composition having sustained toughness MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-06-12 EP claimed
US-4397974-A Low-halogen-content, thermoplastic polyurethane elastomer having improved flame resistance by the addition of a 4-component additive combination, its production and its use BAYER AKTIENGESELLSCHAFT (DE) 1983-08-09 US claimed
US-4146493-A MIXTURE OF HALODIPHENYL OXIDE AND AN ALKYLHALODIPHENYL OXIDE IS BIODEGRADABLE THE DOW CHEMICAL COMPANY (US) 1979-03-27 US claimed