Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL130304 | 0.98 | LTA4H (0.52) | LTA4HTSHRLMNAGAAKMT2A | |
| SCHEMBL8954758 | 0.93 | LTA4H (0.55) | LTA4HTSHRLMNAGAAKMT2A | |
| SCHEMBL28857814 | 0.93 | TSHR (0.48) | LTA4HTSHRLMNAGAAKMT2A | |
| SCHEMBL74839 | 0.90 | ALDH1A1 (0.52) | LTA4HTSHRLMNAGAAKMT2A | |
| SCHEMBL3843172 | 0.88 | ALDH1A1 (0.50) | LTA4HTSHRLMNAGAAKMT2A | |
| SCHEMBL8954774 | 0.87 | MAOB (0.48) | LTA4HTSHRLMNAGAAKMT2A | |
| SCHEMBL3040454 | 0.85 | ALDH1A1 (0.47) | LMNAKMT2AALDH1A1HTTMAPK1 | |
| SCHEMBL5567756 | 0.85 | NCOA1 (0.47) | LTA4HTSHRLMNAGAAKMT2A | |
| SCHEMBL3839158 | 0.84 | ALDH1A1 (0.44) | LMNAGAAKMT2AALDH1A1HTT | |
| SCHEMBL3845666 | 0.84 | SLC6A4 (0.53) | TSHRLMNAKMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7459555-B2 | Photochromic naphthopyrans | RODENSTOCK GMBH (DE) | 2008-12-02 | — | — | US | disclosed |
| US-20020052499-A1 | Photochromic naphthopyrans | OPTISCHE WERKE G. RODENSTOCK | 2002-05-02 | — | — | US | disclosed |
| US-6342459-B1 | PHOTOCHROMIC COMPOUNDS AND ARTICLES OF RESIN FOR OPTHTHALMIC LENSES | OPTISCHE WERKE G. RODENSTOCK (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6331625-B1 | EYEGLASS LENSES; RAPID COLOR AND BRIGHTNESS ADJUSTMENT | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-12-18 | — | — | US | disclosed |
| US-6225466-B1 | FOR ARTICLES MADE OF SYNTHETIC RESIN MATERIALS; RAPID DARKENING AND BRIGHTENING RATES, DURABILITY | OPTISCHE WERKE G. RODENSTOCK (DE) | 2001-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020052499-A1 | Photochromic naphthopyrans | BPNT1, NR2E3, BRIX1 | LTA4H 1700/4885TSHR 2981/4885LMNA 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.