SCHEMBL13031056

SCHEMBL13031056

CC(=O)NC1[C@H](OCc2ccccc2)OC(COC(=O)c2ccccc2)[C@@H](C)[C@@H]1OC(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 3/20 0.52
▸ LMNA P02545 3/20 0.49
▸ KMT2A Q03164 3/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.45
▸ NT5E P21589 1/20 0.42
▸ MEN1 O00255 1/20 0.40
▸ USP2 O75604 1/20 0.40
▸ SLC6A2 P23975 1/20 0.39
▸ SLC6A3 Q01959 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ SSTR1 P30872 1/20 0.39
▸ SSTR2 P30874 1/20 0.39
▸ SSTR4 P31391 1/20 0.39
▸ SSTR3 P32745 1/20 0.39
▸ SSTR5 P35346 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13031053 0.92 POLB (0.61) POLBLMNAKMT2AL3MBTL1NT5E
SCHEMBL6810337 0.88 POLB (0.55) POLBLMNAKMT2AL3MBTL1NT5E
SCHEMBL6810335 0.86 POLB (0.52) POLBLMNAKMT2AL3MBTL1SSTR1
SCHEMBL15143128 0.81 L3MBTL1 (0.50) POLBLMNAKMT2AL3MBTL1SSTR1
SCHEMBL5428265 0.81 SSTR5 (0.47) POLBLMNAKMT2AL3MBTL1SSTR1
SCHEMBL15504415 0.81 POLB (0.58) POLBLMNAKMT2AL3MBTL1SSTR1
SCHEMBL19786845 0.80 LMNA (0.53) POLBLMNAKMT2AL3MBTL1MEN1
SCHEMBL5028352 0.80 PTPN1 (0.54) POLBKMT2AL3MBTL1NT5EMEN1
SCHEMBL4402910 0.80 FGF2 (0.41) POLBLMNAKMT2ANT5EMEN1
SCHEMBL17850343 0.80 LMNA (0.57) POLBLMNAKMT2AL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100286067-A1 GLYCOCONJUGATION OF POLYPEPTIDES USING OLIGOSACCHARYLTRANSFERASES BIOGENERIX AG (DE) 2010-11-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286067-A1 GLYCOCONJUGATION OF POLYPEPTIDES USING OLIGOSACCHARYLTRANSFERASES GALNT2, GALNT6, GALNT1 POLB 1053/4885LMNA 951/4885KMT2A 3613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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