Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | CA1 | P00915 | 3/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7924841 | 0.95 | KDM4E (0.62) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Trifluoroacetic Acid SCHEMBL2650961 | 0.91 | KDM4E (0.57) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL9717434 | 0.90 | MAPK1 (0.71) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL6263089 | 0.89 | MAPK1 (0.72) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL8435925 | 0.88 | MAPK1 (0.81) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL6258138 | 0.86 | MAPK1 (0.84) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL28757390 | 0.86 | MAPK1 (0.84) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL9344489 | 0.86 | KDM4E (0.68) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL13113134 | 0.84 | LMNA (0.59) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL3211210 | 0.83 | CA1 (0.63) | MAPTHIF1ACA1CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720536-B1 | USE OF AMINOSALICYLATES IN DIARRHOEA-PREDOMINENT IRRITABLE BOWEL SYNDROME | PHARMATEL R & D PTY LTD AS TRUSTEE FOR THE PHARMATEL R & D TRUST (AU) | 2012-04-25 | — | — | EP | claimed |
| US-7271253-B1 | Safe process for the preparation of balsalazide | APOTEX PHARMACHEM INC. (CA) | 2007-09-18 | — | — | US | claimed |
| US-20060110743-A1 | Drug evolution: drug design at hot spots | KONISHI YASUO | 2006-05-25 | — | — | US | claimed |
| WO-2002095393-A2 | DRUG EVOLUTION: DRUG DESIGN AT HOT SPOTS | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2002-11-28 | — | — | WO | claimed |
| US-5757408-A | PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING | XEROX CORPORATION (US) | 1998-05-26 | — | — | US | claimed |
| US-5683793-A | Ink jet transparencies | XEROX CORPORATION (US) | 1997-11-04 | — | — | US | claimed |
| US-5589277-A | INK JET PRINTING, AQUEOUS INKS, FAST DRYING | XEROX CORPORATION (US) | 1996-12-31 | — | — | US | claimed |
| EP-0667246-A1 | Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds | XEROX CORPORATION (US) | 1995-08-16 | — | — | EP | claimed |
| CN-113970607-B | Detection method of related substances in balsalazide sodium capsules | 马应龙药业集团股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-3762365-B1 | METHODS AND COMPOSITIONS OF ISOINDOLINE-1,3-DIONE AND ISOINDOLE PRODRUGS USEFUL FOR TREATING CANCER, ULCERATIVE COLITIS AND RELATED INFLAMMATORY DISEASES | AMGEN EUROPE GMBH (CH) | 2024-02-21 | — | — | EP | disclosed |
| EP-3979991-B1 | COLONIC RELEASE FOOD SUPPLY AS A COADJUVANT IN THE TREATMENT AND PREVENTION OF COLONIC DISORDERS CAUSED BY A SUSPECTED OR CONFIRMED ALTERATION OF THE INFLAMMATORY PATTERN AND MICROBIOTA DESTABILIZATION | CRISTALFARMA S R L (IT) | 2023-11-15 | — | — | EP | disclosed |
| WO-2023201044-A2 | JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-10-19 | — | — | WO | disclosed |
| EP-3450506-B1 | THERMOPLASTIC ELASTOMER COMPOSITION, PRODUCTION METHOD THEREFOR, AND ELASTOMER MOLDED BODY | JXTG NIPPON OIL & ENERGY CORP (JP) | 2023-10-18 | — | — | EP | disclosed |
| CN-115536638-B | Triazole compound and application thereof | 上海交通大学 | 2023-10-13 | — | — | CN | disclosed |
| US-5354499-A | Reaction products of lyotropic liquid crystal salt complexes | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |
| US-5354496-A | Lyotropic liquid crystal salt/inorganic compound complexation products | ELLIOTT STANLEY B (US) | 1994-10-11 | — | — | US | disclosed |
| US-5082588-A | Hygrometers | ELLIOTT STANLEY B (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0456093-A2 | Biguanide derivatives and biocidal compositions containing them | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| US-4975249-A | Optical and capacitance type, phase transition, humidity-responsive devices | ELLIOTT STANLEY B (US) | 1990-12-04 | — | — | US | disclosed |
| US-4412992-A | 2-Hydroxy-5-phenylazobenzoic acid derivatives and method of treating ulcerative colitis therewith | BIOREX LABORATORIES LIMITED (GB) | 1983-11-01 | — | — | US | disclosed |