Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868326 | 0.87 | POLB (0.69) | L3MBTL1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL30142131 | 0.87 | POLB (0.69) | L3MBTL1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL8184241 | 0.86 | RAB9A (0.59) | L3MBTL1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL16675417 | 0.83 | POLB (0.56) | L3MBTL1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL181049 | 0.82 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1KDM4ETSHRRAB9A | |
| Azobenzene SCHEMBL28886104 | 0.80 | POLB (0.60) | L3MBTL1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL11174918 | 0.77 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1KDM4EPOLBTSHR | |
| SCHEMBL31538458 | 0.76 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL6266108 | 0.75 | POLB (0.69) | L3MBTL1ALDH1A1POLBTSHRCASP3 | |
| SCHEMBL8415759 | 0.75 | HTT (0.59) | ALDH1A1KDM4ETDP1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298314-A1 | NOVEL JNK INHIBITORS | SCHERING CORPORATION | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298314-A1 | NOVEL JNK INHIBITORS | MAPK1, MAPKAPK2, MAP4K2 | L3MBTL1 2666/4885ALDH1A1 1430/4885KDM4E 3905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.