Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595579 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HSD17B10TSHRNAPRTKDM4E | |
| SCHEMBL13460683 | 0.84 | NAPRT (0.53) | ALDH1A1HSD17B10TSHRNAPRTKDM4E | |
| SCHEMBL30811268 | 0.83 | NAPRT (0.54) | ALDH1A1HSD17B10TSHRNAPRTKDM4E | |
| SCHEMBL29571304 | 0.83 | TSHR (0.63) | ALDH1A1HSD17B10TSHRHTTNPC1 | |
| SCHEMBL109206 | 0.83 | TSHR (0.63) | ALDH1A1HSD17B10TSHRHTTNPC1 | |
| SCHEMBL13035501 | 0.82 | L3MBTL1 (0.56) | ALDH1A1TSHRNAPRTKDM4EHTT | |
| SCHEMBL12441324 | 0.81 | NAPRT (0.50) | ALDH1A1HSD17B10NAPRTKDM4EHTT | |
| SCHEMBL1737254 | 0.81 | BRD4 (0.61) | ALDH1A1HSD17B10TSHRHTTNPC1 | |
| SCHEMBL29870373 | 0.81 | BRD4 (0.61) | ALDH1A1HSD17B10TSHRHTTNPC1 | |
| SCHEMBL162019 | 0.81 | TSHR (0.61) | ALDH1A1HSD17B10TSHRKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240239765-A1 | GLYCINE N-METHYLTRANSFERASE SPECIFIC ENHANCER AND PREPARATION METHOD AND USES THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2024-07-18 | — | — | US | claimed |
| CN-118144374-A | Metal composite waterproof board and preparation method thereof | 河北宇阳泽丽防水材料有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-114981258-B | Glycine N-methyltransferase enhancer, preparation method and application thereof | 高雄医学大学 | 2024-04-19 | — | — | CN | claimed |
| EP-4269401-A1 | GLYCINE N-METHYLTRANSFERASE ENHANCER, PREPARATION METHOD THEREFOR AND USE THEREOF | Kaohsiung Medical University (TW) | 2023-11-01 | — | — | EP | claimed |
| CN-112939970-A | Pyridopyrimidinone derivative, preparation method thereof and application thereof in antitumor drugs | 林剑雄 | 2021-06-11 | — | — | CN | claimed |
| US-12441724-B2 | Inhibitors of plasma kallikrein and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2025-10-14 | — | — | US | disclosed |
| CN-116120313-B | Pyridoimidazole nitrogen fused ring compound and preparation method and application thereof | 遵义医科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-115697993-B | Pyrimidine compounds as AXL inhibitors | 南京正大天晴制药有限公司 | 2024-12-10 | — | — | CN | disclosed |
| US-20240382482-A1 | PLASMA KALLIKREIN INHIBITORS | TAKEDA PHARMACEUTICALS CO (JP) | 2024-11-21 | — | — | US | disclosed |
| US-20240294524-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PDK1 INHIBITORS | OXFORD FINANCE LLC, AS COLLATERAL AGENT | 2024-09-05 | — | — | US | disclosed |
| US-20240239765-A1 | GLYCINE N-METHYLTRANSFERASE SPECIFIC ENHANCER AND PREPARATION METHOD AND USES THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2024-07-18 | — | — | US | disclosed |
| CN-118144374-A | Metal composite waterproof board and preparation method thereof | 河北宇阳泽丽防水材料有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-1095374-A | Biphenyl derivatives, their preparation and they are in the application for the treatment of hypertension and cardiac disease | SANKYO CO (JP) | 1994-11-23 | — | — | CN | disclosed |
| US-5294612-A | Hypotensive agents and cardiovascular disorders | STERLING WINTHROP INC. (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0316668-B1 | USE OF A TETRAHYDRO-PYRIDO(2,3-D)PYRIMIDINE FOR OBTAINING AN ANALGETIC AGENT | MERCK PATENT GmbH (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0404190-A1 | Condensed heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0316668-A2 | Use of a tetrahydro-pyrido(2,3-d)pyrimidine for obtaining an analgetic agent | MERCK PATENT GmbH (DE) | 1989-05-24 | — | — | EP | disclosed |
| EP-0227431-A1 | Heterocyclic amides | BEECHAM GROUP PLC (GB) | 1987-07-01 | — | — | EP | disclosed |
| US-4447256-A | POSTEMERGENCE HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4220771-A | MORPHINE POTENTIATORS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1980-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240294524-A1 | HETEROCYCLIC COMPOUNDS USEFUL AS PDK1 INHIBITORS | PDK1, PDK2, PDK3 | ALDH1A1 2362/4885HSD17B10 530/4885TSHR 3323/4885 |
| US-12441724-B2 | Inhibitors of plasma kallikrein and uses thereof | KLKB1, KLK1, KLK5 | ALDH1A1 3157/4885HSD17B10 1520/4885TSHR 4177/4885 |
| US-20240382482-A1 | PLASMA KALLIKREIN INHIBITORS | KLKB1, KLK5, KLK1 | ALDH1A1 3175/4885HSD17B10 1036/4885TSHR 3852/4885 |
| US-20240239765-A1 | GLYCINE N-METHYLTRANSFERASE SPECIFIC ENHANCER AND PREPARATION METHOD AND USES THEREOF | GNMT, NNMT, HNMT | ALDH1A1 1877/4885HSD17B10 1960/4885TSHR 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.