Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 9/20 | 0.42 |
| ▸ | HTR3A | P46098 | 3/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTR1D | P28221 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13036100 | 0.88 | HTR4 (0.40) | HTR4HTR3AHTR2CCYP2D6CYP2C9 | |
| SCHEMBL8287809 | 0.88 | HTR4 (0.46) | HTR4HTR3AHTR2CCYP2D6CYP2C9 | |
| SCHEMBL13036098 | 0.86 | HTR4 (0.52) | HTR4HTR3AHTR2CCYP2D6CYP2C9 | |
| SCHEMBL8501145 | 0.85 | HTR4 (0.37) | HTR4HTR3AHTR2CCYP2D6CYP2C9 | |
| SCHEMBL8501152 | 0.85 | HTR4 (0.37) | HTR4HTR3AHTR2CCYP2D6CYP2C9 | |
| Water SCHEMBL8828924 | 0.77 | HTR4 (0.51) | HTR4HTR3AHTR2CCYP2D6CYP2C9 | |
| SCHEMBL8499970 | 0.77 | GPR119 (0.33) | HTR4HTR3AADRA2CADRA1AKCNH2 | |
| SCHEMBL8499965 | 0.77 | GPR119 (0.33) | HTR4HTR3AADRA2CADRA1AKCNH2 | |
| SCHEMBL8287812 | 0.76 | HTR4 (0.43) | HTR4HTR3AHTR2CCYP2D6CYP2C9 | |
| SCHEMBL14280207 | 0.75 | HTR4 (0.53) | HTR4HTR3AHTR2CCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7834010-B2 | Modulators of peripheral 5-HT receptors | SERODUS AS (NO) | 2010-11-16 | — | — | US | disclosed |
| US-7834010-B2 | Modulators of peripheral 5-HT receptors | SERODUS AS (NO) | 2010-11-16 | — | — | US | disclosed |
| US-20070254874-A1 | Modulators of Preripheral 5-Ht Receptors | BIO-MEDISINSK INNOVASJON (NO) | 2007-11-01 | — | — | US | disclosed |
| US-20070254874-A1 | Modulators of Preripheral 5-Ht Receptors | BIO-MEDISINSK INNOVASJON (NO) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254874-A1 | Modulators of Preripheral 5-Ht Receptors | HTR4, HTR5A, HTR6 | HTR4 1/4885HTR3A 9/4885HTR2C 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.