Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | WRN | Q14191 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | DGKA | P23743 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30944141 | 0.83 | HTT (0.38) | GAAHTTALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27410760 | 0.83 | ALDH1A1 (0.36) | GAAHTTKDM4ENAAAALDH1A1 | |
| SCHEMBL28715109 | 0.80 | LMNA (0.38) | CYP2C19LMNA | |
| SCHEMBL8448307 | 0.77 | CYP4F2 (0.45) | GAAKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL3007160 | 0.77 | ALDH1A1 (0.37) | KDM4EALDH1A1HPGDLMNAMAPK1 | |
| SCHEMBL4381007 | 0.77 | SMN1; SMN2 (0.52) | GAAHPGDL3MBTL1SMN1; SMN2 | |
| SCHEMBL4385060 | 0.75 | CYP1A2 (0.46) | CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL3010143 | 0.75 | TSHR (0.45) | GAAKDM4ENAAAALDH1A1CYP1A2 | |
| SCHEMBL889268 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNADGKAMAPK1SMN1; SMN2 | |
| SCHEMBL7974811 | 0.75 | TDP1 (0.51) | ALDH1A1CYP1A2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524783-B2 | Polymer micelles containing anthracylines for the treatment of cancer | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2013-09-03 | — | — | US | disclosed |
| US-20100278928-A1 | POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER | INTEZYNE TECHNOLOGIES, INCORPORATED (US) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278928-A1 | POLYMER MICELLES CONTAINING ANTHRACYLINES FOR THE TREATMENT OF CANCER | ABCB4, TOP2A, ANXA5 | GAA 1429/4885HTT 1346/4885KDM4E 1500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.