Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 9/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 5/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13040084 | 0.90 | ADRB2 (0.56) | ADRB2ADRB1TSHRLMNAADRA1A | |
| SCHEMBL13077521 | 0.87 | ADRB2 (0.58) | ADRB2ADRB1TSHRLMNAADRA1A | |
| SCHEMBL13040085 | 0.86 | ADRB2 (0.43) | ADRB2ADRB1TSHRLMNAADRA1A | |
| SCHEMBL13040076 | 0.85 | ADRB2 (0.55) | ADRB2ADRB1TSHRLMNAADRA1A | |
| SCHEMBL14571131 | 0.80 | HTR1A (0.55) | ADRB2ADRB1ADRA1AHTR1AADRB3 | |
| SCHEMBL13040107 | 0.80 | HTR1A (0.55) | ADRB2ADRB1ADRA1AHTR1AADRB3 | |
| SCHEMBL13077540 | 0.78 | ADRB2 (0.58) | ADRB2ADRB1TSHRLMNAADRA1A | |
| SCHEMBL13040078 | 0.75 | ADRB2 (0.41) | ADRB2ADRB1TSHRLMNAADRA1A | |
| SCHEMBL13077526 | 0.74 | ADRB2 (0.57) | ADRB2ADRB1TSHRLMNAADRA1A | |
| SCHEMBL13077494 | 0.73 | ADRB2 (0.44) | ADRB2ADRB1TSHRLMNAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825263-B2 | Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive | NICOX S.A. (FR) | 2010-11-02 | — | — | US | disclosed |
| US-20070072854-A1 | Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive | NICOX S.A. (FR) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072854-A1 | Nitrooxyderivatives of carvedilol and other beta blockers as antihypertensive | ADRB2, ADRB1, ADRA2B | ADRB2 1/4885ADRB1 2/4885TSHR 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.