SCHEMBL13040960

SCHEMBL13040960

O=C1C=CC(=O)N1c1ccc(Cc2ccc(N3C(=O)CC(Nc4ccc(O)cc4)C3=O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 9/20 0.59
MAPT P10636 10/20 0.56
SPHK2 Q9NRA0 1/20 0.51
SPHK1 Q9NYA1 1/20 0.51
ALDH1A1 P00352 9/20 0.50
HTT P42858 2/20 0.50
KDM4E B2RXH2 2/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
MGLL Q99685 2/20 0.49
FAAH O00519 1/20 0.49
ALOX12 P18054 2/20 0.48
MAPK1 P28482 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
HSP90AA1 P07900 1/20 0.47
PKM P14618 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13040961 0.94 GAA (0.65) GAAMAPTSPHK2SPHK1ALDH1A1
SCHEMBL16615639 0.94 MAPT (0.63) GAAMAPTSPHK2SPHK1ALDH1A1
SCHEMBL26050574 0.87 HTT (0.49) GAAMAPTSPHK2SPHK1ALDH1A1
SCHEMBL14159537 0.82 MAPT (0.84) GAAMAPTSPHK2SPHK1ALDH1A1
SCHEMBL18538548 0.81 MGLL (0.58) GAAMAPTSPHK2SPHK1ALDH1A1
SCHEMBL26050589 0.80 HTT (0.54) GAAMAPTSPHK2SPHK1ALDH1A1
SCHEMBL28494489 0.78 MGLL (0.81) KMT2AMGLLFAAHMAPK1TDP1
SCHEMBL14159540 0.73 MGLL (0.62) GAAMAPTALDH1A1MEN1KMT2A
SCHEMBL23489481 0.71 MGLL (0.58) MAPTALDH1A1HTTMEN1KMT2A
SCHEMBL16675654 0.70 MGLL (0.57) GAAALDH1A1MGLLFAAHALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10604641-B2 Thermosetting resin composition and prepreg and laminate both made with the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2020-03-31 US disclosed
US-20170022353-A1 THERMOSETTING RESIN COMPOSITION AND PREPREG AND LAMINATE BOTH MADE WITH THE SAME RESONAC CORPORATION (JP) 2017-01-26 US disclosed
US-20170022353-A1 THERMOSETTING RESIN COMPOSITION AND PREPREG AND LAMINATE BOTH MADE WITH THE SAME RESONAC CORPORATION (JP) 2017-01-26 US disclosed
EP-2226349-B1 THERMOSETTING RESIN COMPOSITION AND PREPREG AND LAMINATE BOTH MADE WITH THE SAME HITACHI CHEMICAL CO LTD (JP) 2014-01-15 EP disclosed
US-20100279129-A1 THERMOSETTING RESIN COMPOSITION AND PREPREG AND LAMINATE BOTH MADE WITH THE SAME. HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-11-04 US disclosed
US-20100279129-A1 THERMOSETTING RESIN COMPOSITION AND PREPREG AND LAMINATE BOTH MADE WITH THE SAME. HITACHI CHEMICAL COMPANY, LTD. (JP) 2010-11-04 US disclosed
EP-2226349-A1 THERMOSETTING RESIN COMPOSITION AND PREPREG AND LAMINATE BOTH MADE WITH THE SAME Hitachi Chemical Company, Ltd. (JP) 2010-09-08 EP disclosed