SCHEMBL16675654

SCHEMBL16675654

CC(C)C1CC(=O)N(c2ccc(Cc3ccc(N4C(=O)C=CC4=O)cc3)cc2)C1=O

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 7/20 0.57
FAAH O00519 3/20 0.57
GAA P10253 2/20 0.43
ALDH1A1 P00352 4/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
LMNA P02545 3/20 0.39
HSP90AA1 P07900 1/20 0.39
CCR6 P51684 1/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
POLB P06746 1/20 0.38
KCNH2 Q12809 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675655 0.93 GAA (0.48) MGLLFAAHGAAALDH1A1HPGD
SCHEMBL18700229 0.86 GAA (0.43) MGLLFAAHGAAALDH1A1LMNA
SCHEMBL16118177 0.83 ALDH1A1 (0.50) MGLLGAAALDH1A1HPGDLMNA
SCHEMBL14159540 0.82 MGLL (0.62) MGLLFAAHGAAALDH1A1HPGD
SCHEMBL14750419 0.81 MGLL (0.50) MGLLFAAHGAAALDH1A1HPGD
SCHEMBL23489481 0.80 MGLL (0.58) MGLLFAAHALDH1A1HPGDHSP90AA1
SCHEMBL18538548 0.80 MGLL (0.58) MGLLFAAHGAAALDH1A1ALOX12
SCHEMBL16118178 0.78 GAA (0.49) GAAALDH1A1HPGDALOX12LMNA
SCHEMBL22632065 0.78 ALDH1A1 (0.56) GAAALDH1A1HPGDALOX12LMNA
SCHEMBL20341015 0.77 MGLL (0.51) MGLLFAAHALDH1A1HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10035926-B2 Ionic liquid catalysts in sulfur-containing polymer compositions PRC—DeSoto International, Inc. (US) 2018-07-31 US disclosed
US-10035926-B2 Ionic liquid catalysts in sulfur-containing polymer compositions PRC—DeSoto International, Inc. (US) 2018-07-31 US disclosed
US-10011751-B2 Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions PRC-DESOTO INTERNATIONAL, INC. (US) 2018-07-03 US disclosed
US-10011751-B2 Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions PRC-DESOTO INTERNATIONAL, INC. (US) 2018-07-03 US disclosed
US-20170306181-A1 IONIC LIQUID CATALYSTS IN SULFUR-CONTAINING POLYMER COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. 2017-10-26 US disclosed
US-20170306181-A1 IONIC LIQUID CATALYSTS IN SULFUR-CONTAINING POLYMER COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. 2017-10-26 US disclosed
US-9617365-B2 Catalytic compositions and thiolene-based compositions with extended pot life PPG INDUSTRIES OHIO, INC. (US) 2017-04-11 US disclosed
US-9617365-B2 Catalytic compositions and thiolene-based compositions with extended pot life PPG INDUSTRIES OHIO, INC. (US) 2017-04-11 US disclosed
US-9611359-B2 Maleimide-terminated sulfur-containing polymers, compositions thereof, and uses thereof PRC-DESOTO INTERNATIONAL, INC. (US) 2017-04-04 US disclosed
US-9611359-B2 Maleimide-terminated sulfur-containing polymers, compositions thereof, and uses thereof PRC-DESOTO INTERNATIONAL, INC. (US) 2017-04-04 US disclosed
US-20160264697-A1 CATALYTIC COMPOSITIONS AND THIOLENE-BASED COMPOSITIONS WITH EXTENDED POT LIFE PPG INDUSTRIES OHIO, INC. 2016-09-15 US disclosed
US-20160186025-A1 PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS PRC DESOTO INT INC (US) 2016-06-30 US disclosed
US-9328275-B2 Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions PRC DESOTO INTERNATIONAL, INC. (US) 2016-05-03 US disclosed
US-20150252233-A1 PHOSPHINE-CATALYZED. MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2015-09-10 US disclosed
US-20150119549-A1 MALEIMIDE-TERMINATED SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF, AND USES THEREOF PRC-DESOTO INTERNATIONAL, INC. (US) 2015-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10035926-B2 Ionic liquid catalysts in sulfur-containing polymer compositions TST, MGMT, CBS MGLL 358/4885FAAH 2138/4885GAA 3493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.