Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 2/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041625 | 0.87 | ALDH1A1 (0.39) | ALDH1A1PARP1SMN1; SMN2PRKCGPRKCA | |
| SCHEMBL13041643 | 0.85 | ALOX15 (0.36) | ALDH1A1KMT2AMEN1HTTSMN1; SMN2 | |
| SCHEMBL13041635 | 0.85 | PARP1 (0.43) | ALDH1A1KMT2APARP1HTTPARP2 | |
| SCHEMBL13041634 | 0.85 | PARP1 (0.43) | ALDH1A1KMT2AMEN1PARP1HTT | |
| SCHEMBL13041639 | 0.84 | PARP1 (0.43) | ALDH1A1LMNAPARP1ADRA2ASMN1; SMN2 | |
| SCHEMBL13041640 | 0.81 | PARP1 (0.44) | PARP1PARP2CHRM2CHRM4CHRM5 | |
| SCHEMBL13041631 | 0.81 | ENPP2 (0.51) | KMT2APARP1SMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL13041641 | 0.80 | BRD4 (0.41) | ALDH1A1LMNAPARP1SMN1; SMN2OPRM1 | |
| SCHEMBL13015326 | 0.80 | BRD4 (0.42) | ALDH1A1KMT2ALMNAPARP1SMN1; SMN2 | |
| SCHEMBL7885143 | 0.79 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1LMNAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278835-A1 | NOVEL COMPOUNDS 660 | ASTRAZENECA UK LIMITED (GB) | 2010-11-04 | — | — | US | disclosed |
| US-20100278835-A1 | NOVEL COMPOUNDS 660 | ASTRAZENECA UK LIMITED (GB) | 2010-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278835-A1 | NOVEL COMPOUNDS 660 | RB1, RPP30, SARS1 | ALDH1A1 2596/4885KMT2A 4545/4885MEN1 1527/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.