Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54674 | 0.81 | — | — | |
| SCHEMBL2555423 | 0.78 | ALDH1A1 (0.67) | POLBMEN1NPC1MAPTRAB9A | |
| SCHEMBL8587965 | 0.76 | PLAU (0.52) | MAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL4450586 | 0.75 | — | — | |
| SCHEMBL7787732 | 0.74 | TSHR (0.60) | POLBMEN1NPC1MAPTKMT2A | |
| SCHEMBL8588833 | 0.72 | LPL (0.45) | L3MBTL1 | |
| SCHEMBL5664827 | 0.72 | POLB (0.57) | POLBMEN1KMT2ASMN1; SMN2TDP1 | |
| Fluoride Ion SCHEMBL73611 | 0.43 | — | — | |
| SCHEMBL28277758 | 0.43 | — | — | |
| SCHEMBL7618349 | 0.43 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716153-B1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E (US) | 2013-10-09 | — | — | EP | disclosed |
| US-20120157658-A1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E (US) | 2012-06-21 | — | — | US | disclosed |
| US-8053571-B2 | Methods, compositions, and apparatuses for forming macrocyclic compounds | JOHNSON THOMAS E | 2011-11-08 | — | — | US | disclosed |
| US-20100216970-A1 | METHODS, COMPOSITIONS, AND APPARATUSES FOR FORMING MACROCYCLIC COMPOUNDS | JOHNSON THOMAS E | 2010-08-26 | — | — | US | disclosed |
| US-7709632-B2 | such as porphyrins, chlorins, texaphyrins via cyclization, oligomerization | JOHNSON THOMAS E | 2010-05-04 | — | — | US | disclosed |
| US-20070217965-A1 | Methods, compositions, and apparatuses for forming macrocyclic compounds | JOHNSON THOMAS E | 2007-09-20 | — | — | US | disclosed |