Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 5/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2980489 | 0.89 | PPARG (0.35) | PPARGPPARATBXAS1ALDH1A1LMNA | |
| SCHEMBL2980487 | 0.89 | PPARG (0.35) | PPARGPPARATBXAS1ALDH1A1LMNA | |
| SCHEMBL2981218 | 0.80 | PLA2G4A (0.33) | PPARATBXAS1ALDH1A1 | |
| SCHEMBL2981217 | 0.80 | PLA2G4A (0.33) | PPARATBXAS1ALDH1A1 | |
| SCHEMBL10151877 | 0.78 | PLA2G4A (0.32) | TBXAS1ALDH1A1 | |
| SCHEMBL2966998 | 0.78 | PTGDR2 (0.36) | PPARGPPARAMAOB | |
| SCHEMBL2966995 | 0.78 | PTGDR2 (0.36) | PPARGPPARAMAOB | |
| SCHEMBL685574 | 0.71 | PPARG (0.56) | PPARGPPARAALDH1A1LMNARAB9A | |
| SCHEMBL2978805 | 0.70 | ALDH1A1 (0.42) | ALDH1A1LMNAATMRAB9AMAPT | |
| SCHEMBL13994578 | 0.69 | TBXAS1 (0.36) | PPARGPPARATBXAS1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286144-A1 | HETEROARYL DERIVATIVES | TAKAHASHI YOKO | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286144-A1 | HETEROARYL DERIVATIVES | GPR119, SLC2A1, SLC2A4 | PPARG 430/4885PPARA 489/4885TBXAS1 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.