Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | GABRP | O00591 | 3/20 | 0.56 |
| ▸ | GABRD | O14764 | 3/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.56 |
| ▸ | GABRE | P78334 | 3/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3791923 | 0.92 | NHERF1 (0.63) | NPC1RAB9ACASP3SENP7NHERF1 | |
| SCHEMBL11924504 | 0.89 | GABRP (0.69) | NPC1RAB9ANHERF1NR4A2GABRP | |
| SCHEMBL13043507 | 0.87 | NPC1 (0.71) | NPC1RAB9ACASP3SENP7NHERF1 | |
| SCHEMBL11924916 | 0.87 | GABRP (0.71) | NHERF1NR4A2GABRPGABRDGABRA1 | |
| SCHEMBL13042958 | 0.82 | RAB9A (0.72) | NPC1RAB9ACASP3SENP7NR4A2 | |
| SCHEMBL11921534 | 0.82 | RAB9A (1.00) | NPC1RAB9ACASP3SENP7MEN1 | |
| SCHEMBL13044035 | 0.82 | RAB9A (0.58) | NPC1RAB9ACASP3SENP7NHERF1 | |
| SCHEMBL13044605 | 0.82 | RAB9A (0.76) | NPC1RAB9ACASP3SENP7NR4A2 | |
| SCHEMBL13044596 | 0.80 | MAPT (0.54) | NPC1RAB9ANHERF1GABRPGABRD | |
| SCHEMBL13044600 | 0.79 | RAB9A (0.79) | NPC1RAB9ACASP3SENP7GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |