Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 2/20 | 0.48 |
| ▸ | GABRD | O14764 | 2/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.48 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.48 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.48 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.48 |
| ▸ | GABRE | P78334 | 2/20 | 0.48 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.48 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.48 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.48 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044632 | 0.92 | MAPT (0.54) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL3791923 | 0.84 | NHERF1 (0.63) | NHERF1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13044029 | 0.81 | NPC1 (0.56) | MAPTALDH1A1LMNAMEN1HTT | |
| SCHEMBL11924504 | 0.81 | GABRP (0.69) | NHERF1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13043190 | 0.80 | NPC1 (0.69) | NHERF1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13043507 | 0.80 | NPC1 (0.71) | NHERF1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11924916 | 0.77 | GABRP (0.71) | NHERF1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL13044046 | 0.76 | MAPT (0.53) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL13044616 | 0.76 | RAB9A (0.68) | MAPTSMN1; SMN2ALDH1A1LMNAMEN1 | |
| SCHEMBL13043227 | 0.75 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010139982-A1 | INDOLE DERIVATIVES FOR THE STIMULATION OF STEM CELL PROLIFERATION | THE UNIVERSITY OF SHEFFIELD (GB) | 2010-12-09 | — | — | WO | disclosed |