Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3747265 | 0.90 | P2RX7 (0.55) | P2RX7DGAT1 | |
| SCHEMBL3748101 | 0.88 | P2RX7 (0.49) | P2RX7DGAT1 | |
| SCHEMBL3739019 | 0.87 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL3743506 | 0.87 | DGAT1 (0.49) | P2RX7DGAT1 | |
| SCHEMBL3754102 | 0.86 | P2RX7 (0.42) | P2RX7 | |
| SCHEMBL3736637 | 0.86 | P2RX7 (0.54) | P2RX7DGAT1 | |
| SCHEMBL3748088 | 0.84 | P2RX7 (0.49) | P2RX7DGAT1 | |
| SCHEMBL3749234 | 0.84 | P2RX7 (0.52) | P2RX7DGAT1 | |
| SCHEMBL3736865 | 0.83 | P2RX7 (0.54) | P2RX7DGAT1 | |
| SCHEMBL3753102 | 0.83 | P2RX7 (0.51) | P2RX7DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292236-A1 | 5-Membered Heterocyclic Amides And Related Compounds | H. LUNDBECK A/S (DK) | 2010-11-18 | — | — | US | disclosed |
| US-20100292236-A1 | 5-Membered Heterocyclic Amides And Related Compounds | H. LUNDBECK A/S (DK) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292236-A1 | 5-Membered Heterocyclic Amides And Related Compounds | GPR35, HCAR2, HCAR1 | P2RX7 268/4885DGAT1 3593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.