SCHEMBL1304345

SCHEMBL1304345

CC(C)(C)c1cccc(C(C)(C)C)c1OC([AlH2])Oc1c(C(C)(C)C)cccc1C(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.43
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TSHR P16473 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
KIF11 P52732 1/20 0.32
KDM4E B2RXH2 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALOX12 P18054 1/20 0.32
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8905124 0.78 CA2 (0.43) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL8905547 0.78 CA2 (0.39) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1304653 0.77 GABRA1 (0.33) GABRA1GABRB2ALDH1A1TSHRKDM4E
SCHEMBL20268794 0.77 CA2 (0.41) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL1033902 0.77 SMN1; SMN2 (0.45) CA2ALDH1A1SMN1; SMN2
SCHEMBL2855727 0.75 CA2 (0.48) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL8905555 0.74 CA2 (0.39) CA2GABRA1GABRB2ALDH1A1TSHR
Hydrochloric Acid SCHEMBL28500978 0.73 CA2 (0.46) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL3096012 0.72 CA2 (0.50) CA2GABRA1GABRB2ALDH1A1TSHR
SCHEMBL727580 0.71 CA2 (0.44) CA2GABRA1GABRB2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0686647-B1 Process for preparing methyl methacrylate with high level of syndiotactic triads ATOCHEM ELF SA (FR) 1998-01-28 EP claimed
US-5656704-A POLYMETHYL METHACRYLATE; HIGH STRENGTH, HEAT RESISTANT, RADIATION TRANSPARENT ELF ATOCHEM S.A. (FR) 1997-08-12 US claimed
EP-3459980-B1 FLUORINE-CONTAINING COPOLYMER DAIKIN IND LTD (JP) 2024-06-19 EP disclosed
US-11780946-B2 Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern TOKYO OHKA KOGYO CO., LTD. (JP) 2023-10-10 US disclosed
US-20210230332-A1 ALTERNATING COPOLYMER, METHOD OF PRODUCING ALTERNATING COPOLYMER, METHOD OF PRODUCING POLYMERIC COMPOUND, AND METHOD OF FORMING RESIST PATTERN NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2021-07-29 US disclosed
EP-2921510-B1 SURFACE TREATMENT COMPOSITION DAIKIN IND LTD (JP) 2019-10-02 EP disclosed
EP-3459980-A1 FLUORINE-CONTAINING COPOLYMER Daikin Industries, Ltd. (JP) 2019-03-27 EP disclosed
US-20190002604-A1 HETERORING-CONTAINING SILOXANE POLYMER, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT DAINIPPON INK & CHEMICALS (JP) 2019-01-03 US disclosed
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT DAINIPPON INK & CHEMICALS (JP) 2018-08-09 US disclosed
US-9951166-B2 Fluorine-containing, silicon-containing polymer and surface treatment agent DAIKIN INDUSTRIES, LTD. (JP) 2018-04-24 US disclosed
US-9909027-B2 Surface treatment composition DAIKIN INDUSTRIES, LTD. (JP) 2018-03-06 US disclosed
US-20080081290-A1 RESIST COMPOSITION, RESIN FOR USE IN THE RESIST COMPOSITION, COMPOUND FOR USE IN THE SYNTHESIS OF THE RESIN, AND PATTERN-FORMING METHOD USING THE RESIST COMPOSITION FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
EP-1903394-A1 Resist composition, resin for use in the resist composition, and pattern-forming method using the resist composition FUJIFILM Corporation (JP) 2008-03-26 EP disclosed
US-20060234154-A1 Mixture containing acid generator and free radical catalyst; acrylated ester monomer JSR CORPORATION (JP) 2006-10-19 US disclosed
US-20060166136-A1 Positive resist composition for immersion exposure and pattern-forming method using the same FUJI PHOTO FILM CO., LTD. 2006-07-27 US disclosed
EP-1684119-A2 Positive resist composition for immersion exposure and pattern-forming method using the same FUJI PHOTO FILM CO., LTD. (JP) 2006-07-26 EP disclosed
EP-1602975-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2005-12-07 EP disclosed
EP-0686647-B1 Process for preparing methyl methacrylate with high level of syndiotactic triads ATOCHEM ELF SA (FR) 1998-01-28 EP disclosed
US-5656704-A POLYMETHYL METHACRYLATE; HIGH STRENGTH, HEAT RESISTANT, RADIATION TRANSPARENT ELF ATOCHEM S.A. (FR) 1997-08-12 US disclosed
EP-0686647-A1 Process for preparing methyl methacrylate with high level of syndiotactic triads ELF ATOCHEM S.A. (FR) 1995-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180223181-A1 SILOXANE MONOMER, POLYMER THEREOF, COMPOSITION CONTAINING SAID POLYMER, AND ELECTRONIC ELEMENT ILK, LIMA1, EED CA2 3907/4885GABRA1 3851/4885GABRB2 4116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.