Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.32 |
| ▸ | F2 | P00734 | 3/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13043639 | 0.87 | PSMD14 (0.30) | NPC1MAPTRAB9AKMT2A | |
| SCHEMBL14700368 | 0.87 | — | — | |
| SCHEMBL13043394 | 0.80 | INSR (0.41) | MAPK1NPC1MAPTRAB9APOLB | |
| SCHEMBL13043833 | 0.78 | — | — | |
| SCHEMBL12589392 | 0.76 | MYC (0.40) | MAPK1NPC1MAPTRAB9APOLB | |
| SCHEMBL12725050 | 0.75 | POLB (0.39) | POLB | |
| SCHEMBL13208380 | 0.74 | ALDH1A1 (0.45) | MAPK1NPC1MAPTRAB9APOLB | |
| SCHEMBL10103983 | 0.72 | NPC1 (0.55) | MAPK1NPC1MAPTRAB9APOLB | |
| SCHEMBL2197114 | 0.70 | INSR (0.44) | MAPK1NPC1MAPTRAB9APOLB | |
| SCHEMBL12380601 | 0.69 | ALDH1A1 (0.50) | MAPK1NPC1MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7828858-B2 | Mixture of sulfide dyes | CIBA CORPORATION (US) | 2010-11-09 | — | — | US | disclosed |
| US-20090100610-A1 | Mixture of Sulfide Dyes | CIBA CORPORATION | 2009-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090100610-A1 | Mixture of Sulfide Dyes | KRT18, TST, ARSA | MAPK1 3342/4885NPC1 4813/4885MAPT 1174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.