Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | HPGD | P15428 | 2/20 | 1.00 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NQO2 | P16083 | 4/20 | 0.52 |
| ▸ | F3 | P13726 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368925 | 0.94 | ALDH1A1 (0.89) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL13141933 | 0.94 | KDM4E (0.89) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL8049689 | 0.92 | MAPT (0.85) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL1304422 | 0.92 | MAPT (0.85) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL14823468 | 0.92 | HPGD (0.85) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL8049692 | 0.92 | MAPT (0.85) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL1304425 | 0.92 | MAPT (0.85) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL20012339 | 0.91 | ALDH1A1 (0.82) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL15398944 | 0.91 | ALDH1A1 (0.82) | ALDH1A1KDM4EMAPTHPGDESR1 | |
| SCHEMBL8614831 | 0.90 | ALDH1A1 (0.81) | ALDH1A1KDM4EMAPTHPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790241-B2 | Reagent for enhancing generation of chemical species | Toyo Goesi Co., Ltd. (JP) | 2017-10-17 | — | — | US | disclosed |
| US-9488915-B2 | Reagent for enhancing generation of chemical species | TOYO GOSEI CO., LTD. (JP) | 2016-11-08 | — | — | US | disclosed |
| US-20160145274-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | TOYO GOSEI CO., LTD. (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20150216876-A1 | METHOD FOR TREATING INFLAMMATORY CONDITIONS | NOVELMED THERAPEUTICS, INC. | 2015-08-06 | — | — | US | disclosed |
| US-9040507-B2 | Method for treating inflammatory conditions | NOVELMED THERAPEUTICS, INC. (US) | 2015-05-26 | — | — | US | disclosed |
| US-20150141687-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | OSAKA UNIVERSITY (FIVE PERCENT INTEREST) (JP) | 2015-05-21 | — | — | US | disclosed |
| WO-2009149081-A1 | METHOD FOR TREATING INFLAMMATORY CONDITIONS | NOVELMED THERAPEUTICS, INC. (US) | 2009-12-10 | — | — | WO | disclosed |
| US-5015666-A | With hydroxy or alkoxy substituents on the triarylcyclopropanes | Board of Reagents of the University of Oklahoma (US) | 1991-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160145274-A1 | REAGENT FOR ENHANCING GENERATION OF CHEMICAL SPECIES | CYBB, PPOX, GPX4 | ALDH1A1 375/4885KDM4E 4569/4885MAPT 4405/4885 |
| US-20150216876-A1 | METHOD FOR TREATING INFLAMMATORY CONDITIONS | ESR2, ESRRA, GPER1 | ALDH1A1 1201/4885KDM4E 2988/4885MAPT 2458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.