Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | PLG | P00747 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PLAT | P00750 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18171930 | 0.84 | MEN1 (0.43) | GABRA1GABRB1GABRA2GABRB2F2 | |
| SCHEMBL880200 | 0.80 | GABRA1 (0.56) | GABRA1GABRB1GABRA2GABRB2F2 | |
| SCHEMBL24910068 | 0.79 | TTR (0.51) | MEN1KMT2A | |
| SCHEMBL13044416 | 0.77 | RAPGEF4 (0.37) | GABRA1GABRB1GABRA2GABRB2F2 | |
| SCHEMBL5086984 | 0.76 | CRHBP (0.53) | F2F10PLGPLAUPLAT | |
| SCHEMBL24909370 | 0.75 | TTR (0.60) | GABRA1GABRB1GABRA2GABRB2MEN1 | |
| SCHEMBL24086757 | 0.74 | GABRA1 (0.38) | GABRA1GABRB1GABRA2GABRB2F2 | |
| SCHEMBL1502445 | 0.72 | CYP3A4 (0.58) | GABRA1GABRB1GABRA2GABRB2PTGS2 | |
| SCHEMBL24086818 | 0.71 | MAPT (0.40) | GABRA1GABRB1GABRA2GABRB2F2 | |
| SCHEMBL25403070 | 0.71 | GABRA1 (0.39) | GABRA1GABRB1GABRA2GABRB2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501840-B1 | BRIDGED BI-AROMATIC LIGANDS, COMPLEXES, CATALYSTS, PROCESSES FOR POLYMERIZING AND POLYMERS THEREFROM | SYMYX SOLUTIONS INC (US) | 2010-12-22 | — | — | EP | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-7659415-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX SOLUTIONS, INC. (US) | 2010-02-09 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2008-10-30 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-7241715-B2 | Bridged bi-aromatic ligands, catalysts, processes for polymerizing and polymers therefrom | SYMYX TECHNOLOGIES, INC. (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269470-A1 | Bridged Bi-Aromatic Ligands, Catalysts, Processes For Polymerizing And Polymers Therefrom | WEE1, WASF2, WEE2 | GABRA1 392/4885GABRB1 352/4885GABRA2 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.