Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13044754 | 0.93 | MDM2 (0.34) | MDM2 | |
| SCHEMBL13947012 | 0.84 | PTK2 (0.32) | PTK2 | |
| SCHEMBL13044705 | 0.82 | PTK2 (0.32) | PTK2SCN9A | |
| SCHEMBL13947015 | 0.81 | PTK2 (0.38) | PTK2OPRK1RIPK1 | |
| SCHEMBL13044750 | 0.79 | PTK2 (0.35) | PTK2RIPK1 | |
| SCHEMBL13044788 | 0.78 | PTK2 (0.32) | PTK2OPRK1SCN9ARIPK1 | |
| SCHEMBL11992838 | 0.78 | MDM2 (0.30) | MDM2 | |
| SCHEMBL11922595 | 0.77 | PTK2 (0.34) | PTK2SCN9ARIPK1 | |
| SCHEMBL13044755 | 0.77 | CFTR (0.46) | PTK2RIPK1 | |
| SCHEMBL13044741 | 0.77 | MDM2 (0.32) | SCN9AMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286131-A1 | VIRAL POLYMERASE INHIBITORS | POLR2A, POLR2H, POLR2B | PTK2 4679/4885OPRK1 1495/4885SCN9A 1852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.