Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15746863 | 0.94 | FDPS (0.41) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL28788255 | 0.84 | FDPS (0.46) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL27922642 | 0.84 | FDPS (0.46) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL3653626 | 0.82 | FDPS (0.49) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL16389287 | 0.81 | FDPS (0.45) | FDPSKMT2ACYP2D6MEN1LMNA | |
| Hydrochloric Acid SCHEMBL2201564 | 0.81 | FDPS (0.47) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL5525422 | 0.81 | KMT2A (0.49) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL19124799 | 0.81 | FDPS (0.47) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL2492654 | 0.80 | FDPS (0.44) | FDPSKMT2ACYP2D6MEN1LMNA | |
| SCHEMBL15745594 | 0.80 | FDPS (0.44) | FDPSKMT2ACYP2D6MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275018-A1 | NITROGEN CONTAINING COMPOUNDS | WOCKHARDT LIMITED (IN) | 2014-09-18 | — | — | US | disclosed |
| US-7834006-B2 | antidiabetics; lower blood glucose levels; compounds based on 1H,2H,3H,4H,5H,6H,7H,8H-pyrrolo[3,4-e][1,4]diazepin-6-one | AJINOMOTO CO., INC. (JP) | 2010-11-16 | — | — | US | disclosed |
| US-7834006-B2 | antidiabetics; lower blood glucose levels; compounds based on 1H,2H,3H,4H,5H,6H,7H,8H-pyrrolo[3,4-e][1,4]diazepin-6-one | AJINOMOTO CO., INC. (JP) | 2010-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275018-A1 | NITROGEN CONTAINING COMPOUNDS | NOS2, NOS1, NCF1 | FDPS 282/4885KMT2A 4610/4885CYP2D6 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.