SCHEMBL27747720

SCHEMBL27747720

CC(=O)c1c(O)ccc2c(=O)ccoc12

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.49
CA9 Q16790 1/20 0.49
LMNA P02545 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
KCNA3 P22001 6/20 0.44
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
THRB P10828 1/20 0.41
FTO Q9C0B1 1/20 0.41
KDM4E B2RXH2 1/20 0.38
KCNA2 P16389 1/20 0.37
KCNA5 P22460 1/20 0.37
KCNA1 Q09470 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12663610 0.77 KDM4E (0.50) CA9LMNAALDH1A1HPGDMEN1
SCHEMBL1304537 0.77 ATP1A1 (0.52) LMNAALDH1A1HPGDMEN1KMT2A
SCHEMBL31632297 0.74 KDM4E (0.47) LMNAALDH1A1HPGDMEN1KMT2A
SCHEMBL30776625 0.73 HPGD (0.53) CA9LMNAALDH1A1HPGDKCNA3
SCHEMBL6451162 0.73 THRB (0.70) PTPN1CA9LMNAALDH1A1HPGD
SCHEMBL15676482 0.71 KMT2A (0.54) LMNAALDH1A1HPGDKCNA3MEN1
SCHEMBL24376271 0.71 KDM4E (0.55) PTPN1CA9LMNAALDH1A1HPGD
SCHEMBL11220013 0.70 CA9 (0.53) PTPN1CA9LMNAALDH1A1HPGD
SCHEMBL30903616 0.70 ALDH1A1 (0.52) ALDH1A1HPGDMEN1KMT2AKDM4E
SCHEMBL15211357 0.70 PTPN1 (0.52) PTPN1CA9LMNAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101486713-B Furo[2,3-h] chromene compound and use for preventing platelet aggregation UNIV SHENYANG PHARMACEUTICAL 2013-05-15 CN disclosed
CN-101486713-A Furo[2,3-h] chromene compound and use for preventing platelet aggregation UNIV SHENYANG PHARMACEUTICAL (CN) 2009-07-22 CN disclosed