Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.48 |
| ▸ | MMP9 | P14780 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodobenzene SCHEMBL10592670 | 0.82 | ALDH1A1 (0.44) | MMP2MMP9ALDH1A1CACNA1FMAPT | |
| SCHEMBL4558728 | 0.82 | LMNA (0.38) | MMP2MMP9ALDH1A1CACNA1FMAPT | |
| SCHEMBL22069 | 0.82 | — | — | |
| Phenytoin SCHEMBL8522629 | 0.81 | CYP2C9 (0.79) | MMP2MMP9ALDH1A1CACNA1FMAPT | |
| SCHEMBL12803697 | 0.79 | LMNA (0.36) | MMP2MMP9ALDH1A1CACNA1FMAPT | |
| SCHEMBL6162987 | 0.79 | LMNA (0.36) | MMP2MMP9ALDH1A1CACNA1FMAPT | |
| SCHEMBL28470397 | 0.79 | LMNA (0.36) | MMP2MMP9ALDH1A1CACNA1FMAPT | |
| SCHEMBL21196916 | 0.79 | — | — | |
| SCHEMBL753785 | 0.79 | ITGA4 (0.37) | MMP2MMP9ALDH1A1CACNA1FMAPT | |
| SCHEMBL29689738 | 0.79 | LMNA (0.36) | MMP2MMP9ALDH1A1CACNA1FMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053514-B2 | Properties tailoring in silsesquioxanes | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-11-08 | — | — | US | disclosed |
| US-20100222503-A1 | Properties Tailoring In Silsesquioxanes | NATIONAL SCIENCE FOUNDATION | 2010-09-02 | — | — | US | disclosed |
| WO-2010062695-A2 | PROPERTIES TAILORING IN SILSESQUIOXANES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-06-03 | — | — | WO | disclosed |