Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28637158 | 0.88 | CYP1A1 (0.42) | TDP1ALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL19490623 | 0.86 | LTA4H (0.50) | HTTALDH1A1SMN1; SMN2MAPTMEN1 | |
| SCHEMBL83816 | 0.82 | TDP1 (0.61) | HTTTDP1L3MBTL1ALDH1A1TEAD4 | |
| SCHEMBL407203 | 0.80 | TEAD4 (0.54) | HTTTDP1ALDH1A1SLC6A4TEAD4 | |
| SCHEMBL3757600 | 0.80 | CYP19A1 (0.47) | ALDH1A1SLC6A4SMN1; SMN2MAPTMEN1 | |
| SCHEMBL9505086 | 0.80 | TTR (0.42) | HTTALDH1A1SLC6A4SMN1; SMN2MAPT | |
| SCHEMBL2706825 | 0.78 | SRD5A2 (0.56) | SMN1; SMN2POLB | |
| SCHEMBL15085780 | 0.78 | SMN1; SMN2 (0.60) | HTTTDP1L3MBTL1ALDH1A1TEAD4 | |
| SCHEMBL822034 | 0.78 | ALDH1A1 (0.74) | HTTTDP1L3MBTL1ALDH1A1TEAD4 | |
| SCHEMBL30195024 | 0.78 | ALDH1A1 (0.74) | HTTTDP1L3MBTL1ALDH1A1TEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136940-A1 | NOVEL GLUCOCORTICOID RECEPTOR AGONISTS | PFIZER LIMITED (GB) | 2010-12-02 | — | — | WO | disclosed |
| US-20100303758-A1 | Novel Glucocorticoid Receptor Agonists | GLOSSOP PAUL ALAN | 2010-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303758-A1 | Novel Glucocorticoid Receptor Agonists | NR3C1, NR3C2, MC2R | HTT 4501/4885TDP1 4215/4885L3MBTL1 4858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.